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Lung Cancer Health Center

Medical Reference Related to Lung Cancer

  1. Malignant Mesothelioma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - General Information About Malignant Mesothelioma Treatment

    Prognosis in this disease is difficult to assess consistently because there is great variability in the time before diagnosis and the rate of disease progression. In large retrospective series of pleural mesothelioma patients,important prognostic factors were found to be:[ 1,2 ] Stage. Age. Performance status. Histology. Various surgical procedures may be possible in selected patients,...

  2. Malignant Mesothelioma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage Information for NSCLC

    BackgroundIn NSCLC, the determination of stage is important in terms of therapeutic and prognostic implications. Careful initial diagnostic evaluation to define the location and to determine the extent of primary and metastatic tumor involvement is critical for the appropriate care of patients. In general, symptoms, physical signs, laboratory findings, or perceived risk of distant metastasis lead to an evaluation for distant metastatic disease. Additional tests such as bone scans and computed tomography (CT)/magnetic resonance imaging (MRI) of the brain may be performed if initial assessments suggest metastases or if patients with stage III disease are under consideration for aggressive local and combined modality treatments.Stage has a critical role in the selection of therapy. The stage of disease is based on a combination of clinical factors and pathological factors.[1] The distinction

  3. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Questions or Comments About This Summary

    If you have questions or comments about this summary, please send them to Cancer.gov through the Web site's Contact Form. We can respond only to email messages written in English.

  4. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - General Information About Non-Small Cell Lung Cancer (NSCLC)

    NSCLC is any type of epithelial lung cancer other than small cell lung cancer (SCLC). The most common types of NSCLC are squamous cell carcinoma,large cell carcinoma,and adenocarcinoma,but there are several other types that occur less frequently,and all types can occur in unusual histologic variants. Although NSCLCs are associated with cigarette smoke,adenocarcinomas may be found in ...

  5. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Questions or Comments About This Summary

    If you have questions or comments about this summary, please send them to Cancer.gov through the Web site's Contact Form. We can respond only to email messages written in English.

  6. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - General Information About Lung Cancer

    Lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.The lungs are a pair of cone-shaped breathing organs in the chest. The lungs bring oxygen into the body as you breathe in. They release carbon dioxide, a waste product of the body's cells, as you breathe out. Each lung has sections called lobes. The left lung has two lobes. The right lung is slightly larger, and has three lobes. A thin membrane called the pleura surrounds the lungs. Two tubes called bronchi lead from the trachea (windpipe) to the right and left lungs. The bronchi are sometimes also involved in lung cancer. Tiny air sacs called alveoli and small tubes called bronchioles make up the inside of the lungs. Anatomy of the respiratory system, showing the trachea and both lungs and their lobes and airways. Lymph nodes and the diaphragm are also shown. Oxygen is inhaled into the lungs and passes through the thin membranes of the alveoli and into the bloodstream (see inset).There are two

  7. Malignant Mesothelioma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Limited-Stage Small Cell Lung Cancer Treatment

    Standard Treatment Options for Patients With Limited-Stage Small Cell Lung Cancer (SCLC)Standard treatment options for patients with limited-stage SCLC include the following:Chemotherapy and radiation therapy.Combination chemotherapy alone.Surgery followed by chemotherapy or chemoradiotherapy.Prophylactic cranial irradiation.Chemotherapy and radiation therapyCombined-modality treatment with etoposide and cisplatin with thoracic radiation therapy (TRT) is the most widely used treatment for patients with limited-stage disease (LD) SCLC.Evidence (combined modality treatment):Survival. The following results have been reported in clinical trials:Mature results of prospective randomized trials suggest that combined-modality therapy produces a modest but significant improvement in survival of 5% at 3 years compared with chemotherapy alone.[1,2,3][Level of evidence: 1iiA]Clinical trials have consistently achieved median survivals of 18 to 24 months and 40% to 50% 2-year survival

  8. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Questions or Comments About This Summary

    If you have questions or comments about this summary, please send them to Cancer.gov through the Web site's Contact Form. We can respond only to email messages written in English.

  9. Malignant Mesothelioma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Advanced Malignant Mesothelioma (Stages II, III, and IV)

    Standard treatment options:Symptomatic treatment to include drainage of effusions, chest tube pleurodesis, or thoracoscopic pleurodesis.[1] (Refer to the PDQ summary on Cardiopulmonary Syndromes for more information.)Palliative surgical resection in selected patients.[2,3]Palliative radiation therapy.[4,5]Single-agent chemotherapy. Partial responses have been reported with doxorubicin, epirubicin, mitomycin, cyclophosphamide, cisplatin, carboplatin, and ifosfamide.[6,7,8]Combination chemotherapy (under clinical evaluation).[6,7,9] Information about ongoing clinical trials is available from the NCI Web site. Multimodality clinical trials.[10,11,12,13]Intracavitary therapy. Intrapleural or intraperitoneal administration of chemotherapeutic agents (e.g., cisplatin, mitomycin, and cytarabine) has been reported to produce transient reduction in the size of tumor masses and temporary control of effusions in small clinical studies.[14,15,16] Additional studies are needed to define

  10. Small Cell Lung Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - General Information About Small Cell Lung Cancer

    Some citations in the text of this section are followed by a level of evidence. The PDQ editorial boards use a formal ranking system to help the reader judge the strength of evidence linked to the reported results of a therapeutic strategy. (Refer to the PDQ summary on Levels of Evidence for more information.) Related Summaries Other PDQ summaries containing information related to lung cancer ...

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