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    Locked In Syndrome

    Important
    It is possible that the main title of the report Locked In Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

    Synonyms

    • cerebromedullospinal disconnection
    • de-efferented state
    • pseudocoma

    Disorder Subdivisions

    • None

    General Discussion

    Locked-in syndrome is a rare neurological disorder in which there is complete paralysis of all voluntary muscles except for the ones that control the movements of the eyes. Individuals with locked-in syndrome are conscious and awake, but have no ability to produce movements (outside of eye movement) or to speak (aphonia). Cognitive function is usually unaffected. Communication is possible through eye movements or blinking. Locked-in syndrome is caused by damaged to the pons, a part of the brainstem that contains nerve fibers that relay information to other areas of the brain.

    Resources

    National Rehabilitation Information Center
    8400 Corporate Drive
    Suite 500
    Landover, MD 20785
    United States
    Tel: (301)459-5900
    Fax: (301)459-4263
    Tel: (800)346-2742
    TDD: (301)459-5984
    Email: naricinfo@heitechservices.com
    Internet: http://www.naric.com

    National Stroke Association
    9707 E. Easter Lane
    Suite B
    Centennial, CO 80112
    USA
    Tel: (303)649-9299
    Fax: (303)649-1328
    Tel: (800)787-6537
    Email: info@stroke.org
    Internet: http://www.stroke.org

    NIH/National Institute of Neurological Disorders and Stroke
    P.O. Box 5801
    Bethesda, MD 20824
    Tel: (301)496-5751
    Fax: (301)402-2186
    Tel: (800)352-9424
    TDD: (301)468-5981
    Internet: http://www.ninds.nih.gov/

    United States Society for Augmentative and Alternative Communication
    100 E. Pennsylvania Avenue, Courtyard
    Towson, MD 21286
    USA
    Tel: (877)887-7222
    Email: info@ussaac.org
    Internet: http://www.ussaac.org/

    For a Complete Report:

    This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

    The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

    It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

    This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

    For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

    Last Updated: 8/12/2010
    Copyright 1988, 1989, 1997, 2000, 2010 National Organization for Rare Disorders, Inc.

    WebMD Medical Reference from the National Organization for Rare Disorders

    Last Updated: May 28, 2015
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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