The glomerular filtration rate, or GFR, is a measure of how well your kidneys are cleaning your blood, which can be determined using an estimated GFR test (eGFR).
The test gets its name from the parts of your kidney that filter waste out -- they’re called glomeruli.
Who Needs This Test?
Your doctor may do an eGFR test as part of a regular physical exam, or they might recommend it if you have signs of kidney problems. Those can include:
- Problems peeing, including pain
- Having to go more often or making less pee
- Blood, foam, or a brownish color in your pee
- Swelling or puffiness around your eyes, belly, wrists, or ankles
- Pain in the middle of your back, near your kidneys
Your doctor probably will also want to check your eGFR if you have a condition that affects your kidneys, like certain autoimmune disorders, diabetes, high blood pressure, or heart disease. You may also get an eGFR test if other people in your family have had kidney disease.
How the eGFR Test Works
For the test, a doctor or nurse will take a sample of your blood. Then they’ll send it to a lab to see how much creatinine is in it. To figure out your results, they’ll use a mathematical formula that’s based on the amount they find, along with your age and gender. Older formulas also used race as a factor, but they are being phased out.
In general, an eGFR result below 60 mL/min/1.73 m² can be a sign of kidney disease. But your doctor will be able to give you more specific information about your result, taking all your health information into account.
What Can Affect the Test?
Your result might not be as accurate if you:
- Are under 18
- Are elderly
- Are pregnant
- Have a kidney condition or other serious illnesses
- Have more muscle than average, like a bodybuilder
- Have a disease that lowers your muscle mass
- Follow a vegetarian diet
- Are obese
If you’re in one of those groups, talk with your doctor about how your results might be affected.