I've taken Solodyn 45 mg.(p.m.)for 1 1/2 months and am pleased w/the results. My acne is drying up,the cysts are shrinking, and the redness is going away. However, one of the side effects I'm experiencing is shedding/hair loss and it's very annoying! I'm also extremely tired, having mood swings, and dizzyness. Since I'm using it in conjunction w/Cetaphil Gentle Wash, Spironolactone, and topical Atralin Gel 0.05%. I'm not really sure which of the meds. is working the best and/or which is causing the side effects. Since I'm not allegic to fish, and the side effects of Atralin don't include dizzyness, lethargy, or hair loss, I'm ruling it out. Hopefully, by Dec.(3mos.), I'll be able to stop taking Solodyn, Spiro and maintain a clear complexion w/Atralin. I'm 55 yrs. old and I've been dealing w/acne for 43 yrs. Taking tetracycline, doxycycline, erythromyocin, zithramyocin, accutane, nicomide(zinc & niacin),+ applying topicals:fostex,benzaclin,klaron,differin,& many more, and washing w/purpose, brevoxyl, and cetaphil, blue light treatments, and occasional tanning has cost lots of $$$$$ even w/insurance!! solodyn has been relatively cheap($25 copay)w/rx card which lasts for initial prescription and 2 refills. Read More Read Less