User Reviews for Entyvio (vedolizumab)

My Crohns was severe. I entered remission after 4 months on Entyvio. Ive been symptom free now after 12 mo. Some joint pain and headaches but it beats getting a eventual colostomy bag

On my 2nd infusion...no side effects except tiredness within an inch of my life. Too soon to have a real opinion about the drug but hopeful. â??canâ??t go back to Remicade because of a serious infection.

Even though Entyvio did begin to help my crohns symtoms the side effects were scary for me. No side effects during infusion but 14 hrs later it started. All of a sudden out of no where extreme fatigue and crushing abdomen chest and head pressure with shortness of breath. This came and went in waves for nearly 2 hours before ending. The emergency room found no evidence of heart attack and blew it off as anxiety. Yes I was anxious but it was a response to not being able to breath properly and the thought that i was dying. It happened again nearly 4 days later same scenario. For some this drug works but for me its poison. Never again.Read More Read Less

I've had Crohn's for close to 50 years. I think I've been involved in almost every IBD drug trial available. Of all of them, Remicade was the best during the trial, but after the trial finished and several months past before I could go back on, I'd developed antibodies that kept it from working again. Advise if you are on Remicade and it works for you don't go off unless it stops working. Initially, I did not respond to Entyvio at the 8-week dosing. MY GI doc did battle with the insurance company and got me on 4-week dosing and I'm now very pleased with the outcome. The number of BM's are way down and better formed. I do have some gas, but not unreasonable. The only thing that I could call a side effect is that I've gained significant weight. My Doc says that it's because I'm feeling better, but I'm guessing with a less active GI system, I'm absorbing more nutrition. The only other downside is that Remicade helped heal some of my fistulas, and so far they almost seem worse, but that may be a separate issue. I've read all the comments and must add that in my experience every individual with IBD is different and responds differently to a treatment. Please keep trying, work with your Docs and keep trying. Entyvio works great for me and I hope everyone finds a treatment or medication that works for them. Read More Read Less

Had extreme headaches and now dealing with extreme muscle and joint pain - stopped taking this med two months and still have extreme joint and muscle pain!

I'm remission, but my energy, brain fog, and motivation are worse than when my disease was active and my skin quality has suffered since I've started taking this. I'm always tired.

Hi. I am hoping someone can respond to this. After 1st dose of entyvio I ended up short of breath 4 days after treatment. Within that week I went to ER for the shortness of breath where they found nothing wrong with me. My Dr told me to continue with 2nd infusion. That was 4 days ago and again i cant breathe. Wheezing and dry cough. Been taking benadryl like candy, which does help. Dmean while I have no abdominal pain due to my crohn's. But breathing is important too. Anyone else have this issue ? Does it go away? Get worse ? Thanks for taking the time to read this. Read More Read Less

Has anyone else experienced severe gas and gas pains almost constantly? It started after my second infusion. I'm miserable!

I have to respons on this drugs because I saw another review about anxiety and mood changes. I thought I was the only one who feels anxiety after taken Entyvio for the second time. I am also a lot of times sick from the flu/ not getting weight on. Chronic pain in both thumbs, back and whole body pain after the infusion. There is no other medication what worked for me so all hope on entyvio is gone now. These side effect are really terrible and causes mental problems. I know now that its because of the Entyvio. Believe me, I was not a anxious person at all!Read More Read Less

I started Entyvio in September 2017. At first, the only side effect I had was joint pain. But as the treatments went on, I started experiencing Anxiety. It has gotten so bad that I actually ended up in the ER recently with a Panic Attack. I did not experience Anxiety prior to Entyvio. I also have been experiencing crushing chest pressure (which makes the Anxiety worse) as well as flu/cold like symptoms, fatigue, dizziness/brain fog and extreme joint pain. I've talked with Entyvio directly and they have not had enough reports of Anxiety to lost it as a side effect. If you are experiencing Any side effects, REPORT THEM. Also, I've tried talking to my doctor SEVERAL times about my side effects and he blows me off. Needless to say, I am not continuing Entyvio any longer. The side effects are not worth the benefits. I am currently experiencing a significant improvement in my Crohn's Disease, although I do still experience severe "flair ups."Read More Read Less

50 yr. old female with Chron's. Had to go off Remicade (which worked really well) due to complications with EBV virus. Moved to entyvio. Took 3 "loading doses" to kick in, but is working well. That's all I take now. Had a little joint pain at first, but after 8 months that's faded. It's not on the side effects, but I'm having issues with weight gain and not being able to lose weight despite upping my exercise and lowering my calories. My face has gotten rounder too - but not as bad as when I was on prednisone. Over all it's been a good alternative for me so far. I work in a school, and this has been better on my immune system than the tnf-a blockers and steroids.Read More Read Less

I got diagnosed with severe UC when I was 11 and spent the next 9 years searching for a drug that could achieve remission. Fast forward, now I'm 20, and Entyvio is the only drug that has been able to suppress my symptoms nearly entirely. The only downside is that I took my dose 6 days late due to an out of state funeral trip and it made me very nauseous/caused vomiting much like a 24-hour flu. Other than that, it's been a miracle drug for me!

I am 17 and have had severe UC since I was 14. Nothing has worked for me for over a year but I have been on entyvio for almost half a year now and have had no symptoms at all and no side effects other than fatigue which is not bothersome to me and very much worth it. Hopefully this will continue to be effective for the remainder of my life time and the side effects with remain the same.

Doing great, bowels perfect, but after 3rd infusion I have terrible stomach pain and nausea. Can't eat, lost 11 pounds in a month and pain wakes me even at night.

I received Entyvio for 2 years. Not much improvement. Bleeding often. At the end of 2016, I developed Pleural effusion, pericardial effusion, severe anemia and a persistent cough. I was admitted 3 times. My last infussion was in April4th 2017. Much better now since I discontinued the treatment.

I was switched to Entyvio after getting numerous recurring infections while taking Humira. It has provided significant relief with only occasional flares. The worst part (aside from the high cost) has been the side-effects: ankle/foot tendon tightening

So i have really no change. I am extremely moody though and angry. Lot. I wasn't like this before.

I've been on Entyvio for about 18 months and I'm doing well. I take an anti rejection medication as well. I do have weaknesses and pain in my joints. My treatments were moved to every 6 weeks instead of every 8 weeks and that helped a lot. I do have a bad head ache, sore throats and extreme fatigue for about 24 to 48 hours after my treatment. Otherwise, I have my life back.