After reading through a lot of the feedback, I have to share my experiences and knowledge. With dry eye, frequently comes inflammation of the backside of the upper and lower eyelids - a feeling of sand in the eye, in addition to an irritated and roughened surface of the eye itself. Your eyelid margins can be red, swollen, and very uncomfortable also - AND, you might also have meibomian gland issues. Xiidra works by blocking certain elements that trigger these immune responses - which bring about the uncomfortable inflammation previously described - swollen tissue, itching, roughened tissues, redness, etc. By the time you experience these symptoms, just about anything you put in your eye, is going to be uncomfortable. In addition to prescribing Xiidra - the doctor can also prescribe Lotemax drops or ointment OR Prednisolone Acetate drops - in order to enhance and speed the relief of inflammation and discomfort. The doctor can also add in moisturizing drops as well, as part of the regimen. With blepharitis, can also come staph infections - so the doctor may also prescribe antibiotic drops. Staph brings on inflammatory discomfort as well. Xiidra works much quicker than Restasis, when it comes to relieving the discomfort/symptoms of dry eye inflammation - but nothing brings immediate relief for all of the factors of inflammation that you might have. The dropper itself needs flicked with your finger, until the medicine drops down - and then squeezed with your fingers to release a drop in to your eye. It is quite simple. Practice putting drops in your eye, using an over the counter preservative free ‘moisturizing’ only drop. Do not practice with an antihistamine/decongesting drop. It does take practice getting the drops where they need to go. Regarding the taste - read the directions. You are supposed to place some pressure on the tear duct, so that the drop does not drain in to your sinuses and then down your throat. In order to receive the best treatment for your dry eye - find a doctor that is really up on the subject, has the right diagnostic equipment, and makes treating dry eye a large part of his practice. Xiidra is medicine - it is not a 2 second text message - place a drop in your eye, place pressure on the tear duct, lean back, blink once, and keep your lid closed for about 5 minutes - so that the medication has a chance to do it’s job. There may be a little blurriness - which is temporary - blurriness usually goes along with drops that are thicker than water. These are not “drop and run” drops - this is a serious medicine ritual drop - that takes several minutes, to do it right. Side effects are always possible with every prescription and non-prescription medication. It took some time to develop dry eye - and treatment and healing can take some time, and be frustrating. First, find the right doctor - read up on dry eye yourself, and explore the various treatment modalities. It can take different routes, and a number of tries - before you find what works for you. There is no one size fits all, when it comes to dry eye. I am a licensed professional in a healthcare field, that has been around the block with dry eye - and interacted with many doctors that specialize in the treatment of dry eye, along with a lot of its’ complexities - Some of these doctors have been excellent, and some not so proficient. I am a caregiver, and also a patient. I have come through my own experience - to recognize a fantastic dry eye doctor - versus the not so great practitioners……Good Luck on your journey - and interview any prospective doctor - really evaluate his/her knowledge on the subject - it will make a world of difference in your treatment. Here is a bee in your bonnet - did you know that eating spicy foods, can make a not so pleasant difference in your symptoms?Read More Read Less