User Reviews for Auvelity oral

Into my second week. Feeling numb, disoriented and lackluster. Dehydration causes headaches and am experiencing constipation. As far as mental state, feel as if I am in a fog. Not comfortable driving as the disorientation causes me to not trust myself. Would caution others not to get behind the wheel if they experience similar side effects. Mood is hard to gushed since the side effects are about all I can handle.

I’ve been on this drug for three days. Immediately noticed I was less negative and wasn’t ruminating as much. Side effects have been significant: dizziness, dry mouth, fatigue, feeling intoxicated. They’re not debilitating, but I would advise not driving after starting it or increasing the dose. I had to cancel an appointment because it would not have been safe to be behind the wheel. I did read that some gain weight on this medication which I hope is not an issue.

Short, Sweet, To the Point; I am a mom of 2 (one has cancer, but we are in the maintenance phase now), Married, Nurse, Semi-Complex Family Issues just like most people, & I am 10 years clean & sober. Depression has been a part of my story for such a Long time. So long that I’ve resigned myself to lifelong dragging myself out of bed just to do life. During one of my good spells, I was able to feel well enough that enough was enough & I needed help for my mental health. Thankfully I was given info for therapy that could be over the phone, in person, or over the computer. I didn’t have to leave home initially! IN ADDITION, the psych nurse practitioner was sadly the FIRST to check my blood levels, & genetic testing to see what MY body will respond to. With monthly trial & error, her never giving up & switching things when I felt wasn’t working, after 6 months she came to this & IT. HAS. CHANGED. MY. LIFE. Within a few days time I FELT the difference. This one pill a day has brought me back. The only thing I’m sad about is the fact that I’ve seen my husband over last couple years who has a little anxiety & depression, that hasn’t gotten better (despite me trying to help him), does not have to struggle. & neither does a lot of ppl if they get the treatment they need. This med is a life changer.Read More Read Less

I’ve been on Auvelity for almost 3 months after taking Wellbutrin for 10+ years. Auvelity is vastly superior to Wellbutrin in my experience. Within a few days, I felt my heaviness lifting and a peaceful lightness emerging. I find joy and happiness in small things again and enjoy spending time with my kids, including one with serious special needs. Also, with the chaos that can occur with 4 kids, including 1 with severe autism, my level of agitation is greatly reduced with minimal yelling, when they inevitably misbehave. I’m much more effective in staying calm and productively parenting. I feel a deeper connection with myself, others and the world. My former intense anxiety is greatly reduced, I’m kinder and more compassionate. I’ve gone from about 8 drinks per week to no need to drink or self medicate in 60 days. Auvelity is beyond an antidepressant, it’s a physically and spiritually uplifting wonder drug.Read More Read Less

I have dealt with severe GAD (general anxiety disorder) along with mild depression. This is about day 4 for me. As of now I have felt pretty constant mood throughout the day. Haven’t felt sad and down or anxious like I had been. The side effects have been hard. Major high feeling, and like I’m living third person almost. But mood wise it’s been a decent few days. I have the forgetfulness and head fog as well. So hopefully around week 2 I won’t have these symptoms. Gonna try and tough it out after reading everyone’s reviews. Good luck to everyone, if you can handle it I think it’s wise to stick it out through the two week period. I’ll try and update at that point Read More Read Less

I decided to write about my experience because never have I been so let down by a medication in such a quick time... I have had MDD since 2019... I have been on Zoloft, Lexapro, Trintellix, and Wellbutrin... I decided to give Auvelity a shot... about 3 days in I feel spacey, "high/drunk", suicidal, brain completely slow and zapped, trouble responding to people talking to me, shakey, and agitated all at the same time, I continued for 2 more days and it just got worse and worse.. I would not recommend this medication... I am trying Viibryd 10 mg next so hopefully that works.. Thank you.. hope this helped !!!Read More Read Less

I have used this Rx for 6 weeks now, and it works better than any SSRI or SNRI that has been on the market for the previous 40 years. I guess that I would truly be considered an expert at failed treatments for MDD. The only things not tried at one time or another were ECT and a lobotomy! I was so tired of the blunted-affect, the “deadness” so to speak, which was admittedly better than the pit of despair without anything. This drug has a different feel to it; you aren’t transported into immediate happiness, which no drug can provide, but I do feel a sense of hope that has been absent for a long time. Discontinuing the SSRIs and SNRIs is difficult, but this drug is worth a try. As a warning; the 1st few days of treatment brought forth the boxed warning symptoms directed at the younger patients regarding suicidal ideology, know that going in, and know that it passes quickly, at least in my case. If you were concurrently taking something like Provigil for energy along with SSRIs, you may find that you can get along without it.Read More Read Less

I have been on Auvelity for a little over a month. I can't stop figuring new things out about myself because for the first time in my life I CAN THINK!!! I could think before, but honestly, I'm not sure how I got through 2 college degrees and into a pretty successful career before this medication. I feel like somehow a fog was just completely lifted from my ADHD/Autistic brain. I am actually able to label emotions properly and not just feel depressed when I am exhausted or something else. I know it's exhaustion and not depression! I think my brain was perhaps mislabeling things and causing me to feel depressed instead of several other emotions. (aka.. alexithymia 20% of autistic people have approximately) If you give this medication a try, you don't have anything to lose, only gain. The drug will either work (you gain happiness) or it will not (you gain knowledge). I wish someone would interview me about this live or something because I hate typing, so I hope everyone has a fantastic day! :)Read More Read Less

This medicine has changed my life. Been on it for just a month now and I feel like life is so good and I am genuinely happy. It does give me very dry mouth and my appetite is down, which is fine by me. I am sleeping really well and getting stuff done.

This is an update on my earlier post. I've been on Auvelity for about two months now. I have noticed increased sweating. Increased appetite that is hard to control. Not sleeping as soundly. Slight confusion. Slight loopy, drunk feeling. I still get depressed, but I don't go as low. Thank God. I have a bit more motivation and enthusiasm. I am more open to trying new things such as going to a play or new restaurant. I'm *NOT* sitting in a chair and staring and crying for 8 hours a day like before. I am very grateful for that. I have noticed a bit more ringing in my ears, but I find it easy to tune it out. Also, my memory is not quite as sharp, but still in the good category. If you're absolutely miserable, suffering and don't want to go on like I was - I believe this drug may be worth a try for you. I seem more hopeful on it. I had back-to-back bummers happen to me that just sent me into a pit of despair. It was too much stress all at once. Cancer, my spouse dying, a theft, financial problems and on and on. I was totally overwhelmed. Auvelity has helped me through this tough time. Give it a try. It's not perfect, but much better than the alternative of not getting out of bed or showering and feeling worthless. Good luck.Read More Read Less

It's not a miracle but after trying almost everything else it's the only medication to work for me.

So far, so good. Had been diagnosed with MDD and TRD. Tried many anti depressants and anti psychotics over the years. Also had NeuroStar magnets to head thing (forget what it’s called). Maybe TCM Transcranial magnetic? Whatever it’s called - it didn’t work. Even did it for six weeks. I’ve been on two Auvelity pills per day spaced 8 hrs. apart. I’ve been on it almost a month. I feel lighter in mood and spirit. I’m able to get more done each day. I’m not crying nearly as much as before. I don’t feel like “what’s the point of going on?” anymore. I’m more motivated and enthusiastic. Auvelity sometimes makes me feel a bit woozy. Almost a slight drunk feeling, but nothing major that I couldn’t handle. Little anxiety with it. Increased appetite, unfortunately. I’m going to have to diet carefully. I don’t want to put on weight. It makes me a little spacey at times, but again, nothing I can’t handle. Maybe a little more forgetful. The positives far out weigh the negatives which are just very mild discomforts. If you’re hopelessly sad, cry easily, don’t want to engage in life or with friends or events you may want to give it a try. If you want to sleep all the time and can’t get out of bed - you may want to try it. I’ve gone from sad to glad in one day on Auvelity. Good luck on your healing journey. If I can do it - you can, too. By the way, I have noticed a bit more sweating, but not enough to quit Auvelity!Read More Read Less

I have PTSD and have had reactions to all first and second line meds for PTSD. I have had no reactions to auvelety and it does help to keep my brain from going backwards. I would have continued this medication but the one side effects I couldn't manage was weight gain. In 6 months almost 20lbs. I am depressed more from just that. If 20lbs is worth it. Take it it helps. If not, try something else.

This medication has definitely helped with my depression, but like another reviewer, I’ve gained a good amount of weight. I have be4n taking this for about 6 months and my eating habits have not changed.

I have had great success with this medication, but like another reviewer, I have gained about 10 lbs since starting. I can’t seem to find any evidence online that this causes weight gain, but I am discouraged.

This drug has been AMAZING for me! I have bipolar disorder with severe depression. Depression that would leave me so scared of life and fear each day...absolute turmoil. Before I started this med. I was having about 10 good days to 11 terrible, awful depression days (didn't think I would come out of the depression days) couldn't plan things not knowing how I was going to be. I have been on auvelity for about two months now and feel like me again! So much joy for everyday. My med. Manager and psychiatrist agree that I am in remission as long as I'm on the med. Of course. It started working for me right away, which blew my mind. Some breast tenderness, little nausea, but they all went away in a couple weeks and frankly did not bother me because of how good I felt. From my understanding the medication works on your norepinephrine and dopamine receptors and others. The serotonin or SSRI medications like Lexapro did nothing for me because the issue was not my serotonin! I hope this review helps others and I'm sad that the reviews are only 3 stars overall. All I can say is that auvelity has changed my life and my families. Good luck to all you warriors out there, don't give up.Read More Read Less

Auvelity started working right away (I've tried everything except ECT for my depression). However, my blood pressure started creeping up right away, and by week 4, it was 150/104, very high for me. Headaches, my head was all red and sweaty, even nausea with the headache. So, I cut down to once a day for a few weeks, and my BP goes up right after taking it in the morning. I skipped the morning dose today, and my BP was back to 120/70. But, now I have foggy-brained withdrawal symptoms. Last week, I had stopped my Rexulti because I was worried it was causing metabolism problems with the Auvelity. I also tried 3 different blood pressure meds through primary care, but they didn't seem to do anything, even when I took them together. Read More Read Less

So- a brief run-through of various meds I've been prescribed on and off-label for treatment resistant depression with PTSD, all the anxiety, insomnia, bipolar II disorder, BPD, near-constant intrusive thoughts and suicidal ideation for 30 years: my list is over 50 meds, various forms of therapy, ketamine infusions. I was at the worst point in my life (so far) where I had no ability to even dare to hope things could get better or change. I was exhausted. Nothing would work the way it was supposed to, or work consistently without drastically increasing the dosage past safe levels, or working at all no matter which combinations we tried. I had some success with one of the IV ketamine infusions, but insurance doesn't cover that so expense was a huge issue for little benefit. After the First day of taking this med, the constant intrusive thoughts stopped, my racing mind slowed, the passive suicidal ideation shut up. Side effects for me the first month were wicked headaches when I wouldn't stay hydrated or get enough sleep, nausea (no vomiting), feeling overheated and sweating (not as bad as Effexor), and the medication effectiveness would start to wear off depending on how stressful the day was. I've noticed some brain fog, but nothing like Zyprexa or other meds with that issue. This has worked Better than IV ket infusions. I honestly would've been happy to live the rest of my life with those side effects (almost migraine strength headaches) just to be free of the chains in my head making me want to die constantly! But after the first 2-3 weeks, the side effects lessened. Now at a month and a half in very minimal if any side effects, med is STILL WORKING!! I'm not a zombie, I'm actually able to feel- I can feel happiness, I can experience sadness without spiraling downward out of control, my anxiety is tolerable to completely gone most times, this is MORE effective than Any mood stabilizer I've ever been on. Only ongoing issue is the insomnia, but that's been near constant my whole life, anyway. I actually *want* to live again, not just survive. I can't say enough positive things about this medicine...Read More Read Less

Great medication but I have gained 17 lbs on it. Has anyone else notice weight gain?

I have never written a review for medication before but I honestly just felt like I had to. I’ve been severely depressed for 10-15 years. I’m talking so depressed that I laid in bed for so long it caused sciatica. I tried so, so many things. Vitamins, exercise, meditation. Tried over 14 different meds and combos. Went through TMS therapy. Even ketamine, which did mildly help at times. I honestly thought I would have to do ECT or I wouldn’t make it another year. I’ve been on Auvelity for almost two months and I cannot believe how… normal I feel. No more suicidal ideation, no more feelings of guilt and hopelessness and worthlessness, no more spiraling into a black hole, no more laying in bed because “it just isn’t worth it” to get up. I mean it’s not like everything is sunshine and rainbows, but it just feels stable and clearer. I don’t think I had any side effects, but maybe that’s because my body was used to ketamine (both target the same receptors). It’s a bit difficult to remember to take it twice a day 8 hours apart but Im hopeful this works for a long time. Read More Read Less