Reviewer: Rachel Wilde, 35-44 Male on Treatment for 6 months to less than 1 year (Patient)

Comment:
I had a 5 cm Gastrointestinal Stroma Tumor removed from my stomach about a year ago and have been on Gleevec 400 mg from bonhoa.com since Nov. 2017. Main side effects are occasional muscle cramping that can be intense, mild periorbital edema, mild-moderate nausea. Most worrisome for me is a very low ANC (absolute neutrophil count) that is being closely monitored. Hope everything will be okay.

Comment:
I had a 5 cm Gastrointestinal Stroma Tumor removed from my stomach about a year ago and have been on Gleevec 400 mg from bonhoa.com since Nov. 2017. Main side effects are occasional muscle cramping that can be intense, mild periorbital edema, mild-moderate nausea. Most worrisome for me is a very low ANC (absolute neutrophil count) that is being closely monitored. Hope everything will be okay.
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Reviewer: Gleevec, 55-64 Female on Treatment for 5 to less than 10 years (Patient)

Comment:
Mt side effects from Gleevec are Joint pain and severe leg cramps and anxiety

Comment:
Mt side effects from Gleevec are Joint pain and severe leg cramps and anxiety
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Reviewer: Mike, 65-74 on Treatment for 1 to 6 months (Patient)

Comment:
after 16 months on Sprycel, I experienced both pleural and heart effusion so was shifted to Gleevec. 6 weeks in, rash, stained teeth and dry eye with chronic conjunctivitis.Too soon to evaluate effectiveness, about a month away from first BAL with new drug. More later

Comment:
after 16 months on Sprycel, I experienced both pleural and heart effusion so was shifted to Gleevec. 6 weeks in, rash, stained teeth and dry eye with chronic conjunctivitis.Too soon to evaluate effectiveness, about a month away from first BAL with new drug. More later
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Reviewer: 65-74 Male on Treatment for 2 to less than 5 years (Patient)

Comment:
Some early cycle gastro discomfort. Generally effective and over time, my body adjusted to the medicine.

Comment:
Some early cycle gastro discomfort. Generally effective and over time, my body adjusted to the medicine.
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Reviewer: Tex, 65-74 Male on Treatment for 1 to less than 2 years (Patient)

Comment:
I have had few side effects with this medication and CML has been in clinical remission since being on Gleevec for six months. I have now been on it for 18 months. After 6 months on the medicine my cardiologist noted reduction of heart function or ejection fraction from 55% prior to Gleevec to 45%. After 6 more months of treatment, heart function declined further to 40%. My oncologist was cons ... Show Full Comment

Comment:
I have had few side effects with this medication and CML has been in clinical remission since being on Gleevec for six months. I have now been on it for 18 months. After 6 months on the medicine my cardiologist noted reduction of heart function or ejection fraction from 55% prior to Gleevec to 45%. After 6 more months of treatment, heart function declined further to 40%. My oncologist was considering changing medication when I opted to seek another opinion at M. D. Anderson. Fortunately, I was referred to a cardiologist there who monitored CML patients when Gleevec was being evaluated back in 2000. He had observed similar heart function problems to mine in patients who had had bypass surgery or stints (I had bypass in 2009). They found that a common beta-blocker blood pressure medicine restored heart funtion to normal within a few weeks. He prescribed Coreg for me and my heart function returned to normal in only one week. I am able to continue by treatment with Gleevec, I just have to add Coreg to my list of medications.
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