User Reviews for Zoladex subcutaneous

I know Zoladex is an important drug for my hormone receptive cancer but the side effects are terrible. I don't have much of a memory now, I can't remember short term stuff, my blood pressure has gone so high I am now on BP meds, I have absolutely no sex drive (only in my 40's) and unbelievable hot flushes and up at least 3 times a night. My hair has really thinned out, and I have aches and pains which are quite terrifying! But Zoladex is important in hormone receptive breast cancer, just a bummer about the terrible side effects.Read More Read Less

trouble sleeping , back & chest pain ,breathlessness, concentration

low energy need 1 -2 1 hr naps daily hot and cold flushes sleeplessness at night enlarged breasts weight gain inreased restess leg syndrone some anxiety and depression some oss of mental acuity

I was started on Zoladex without any information about it except that it was a shot. About six weeks after the shot the side effects started. My libedo went to zero,I gained weight all in my belly, I had hair loss, but the worst were the hot flashes. Four an hour was common but the absolute worst was that the hot flashes drasdictly affected my Parkinsons. Up to this point I showed few symptoms by taking medications. The symptoms can no longer be controlled with medication. My balance has gotten much worse and I have uncontrolled movement of my hands and very often with my legs. I was set to have the second shot three months after the first,but refused to take it. It is now ten months after the first shot and all of the side effects are as bad as they have been. I think zoladex should be taken off the market Read More Read Less

I had severe endometriosis and at age 28, underwent lap & laser, then 3 months of Zoladex, then a second lap & laser to get rid of any remaining endo. Side effects were tough - total menopause at age 28! However, the treatment worked like a charm and it was worth every minute. I followed a totally organic diet throughout and actually lost 10 lb while on this drug. I then fell pregnant within 6 weeks of my second lap & laser, and now have 2 beautiful kids and have not had any endo symptoms since. That was 8 years ago. I can't rate this drug (nor my first class OBGYN who did the surgeries) highly enough!Read More Read Less

Taking Zoladex + Tamoxifen for breast cancer. So far, have had no relapses in my breast cancer, so I guess its working. Still, side effects are dire, the worst being severe hot flushes, insomnia, mood swings, depression (although only a couple of days a month), extreme fatigue, no sexual desire, and a terribly dry complexion (I seem to have aged five years in only 12 months). Still, I only have one more year to go, so I guess I just have to weather it through!

Diagnosed with estrogen-positive Breast Cancer in 2003. Did no chemo nor radiotherapy. Changed Lifestyle and diet. Had a relapse in 2010 and first thing my new doctor asked was if I was still having kids. Replied in the negative so he said he needed to stop the periods. Had no objection to this and so he administered first dose of Zoladex. I found out i had also developed fibroids. Started treatment in March 2010. Have seen the change in my condition. First of all, fibroids have shrunk as they no longer press on my bladder. Haven't had any periods and I hope they don't come back. Have hot flushes but they do not last for more than 2 minutes and they are very bearable. Have so much energy, good appetite and sleep well. However I do hope I do not have to continue it for more than a year as every drug has its side effects. Read More Read Less

Male 67+. On a regimen of a shot every 90 days for two years. Have had 4 shots so far. Only side effect would be no libido at all. Other than that nothing. Outcome of 0 PSA supersedes the single side effect.

many hot flashes, easely tired

my dr orginally was giving me the Lupron Depot for endometriosis which worked out great for me and after my insurance changed they would not cover it for breast cancer so I had to get the Zoladex and been suffering from fatique/headaches/pain. I would take the Lupron shot over Zoldex. Less irritation easier to handle but Lupron does not list breast cancer under diagnose. That is a shame

I was on it for 6 months and it worked great. If you have Endometriosis and your doctor wants to put you on this I would recommend it. I have pain 3 weeks out of the month and for 6 months i had no pain at all. It is not the best felling when you are getting the shot in your stomach but i would do it again in a heart beat. Hope this helps anyone who is going to have this treatment.

Works well to reduce PSA levels... Side effects for me are the almost unbearable hot flashes, weight gain, back pain and neuropathy in my hands and feet. I'm also diebetic but the burning and tingling has never been this bad.

cont'd uterine bleeding longer than 30 days, even after add-back therapy of large doses of Estrogen. Frontal Lobe Headaches, worse with bending over. Treatment was to thin the inner lining of the uterus, due to Fibroids and before Uterine Ablation Procedure.

It was so wonderful living pain free while on this injection, having no periods was a bonus too. The only hassle was finding medical staff experienced in administering the injection and found going to the local hospital quite good. Also asked for general anes. cos do not like needles, and this one is big!! The hot flushes were a bit of a pain, but got used to them and prefered them to pain.

has had one side effect...about 3 weeks after injection has bad mood swings and violent behavior. Dr's have no idea why this is. PSA level started out 6 months ago at 12+ now it's almost less than 1 bur we have these mood swings that are HORRIFIC....

I could not tolerate Tamoxifin after my cancer treatment, so I have been receiving the injection for 9 months. I find the injection to be painfull for the first several days and the bruising last for several weeks. The first several days I can experience nauseau, hot flashes, and fatigue. I have gained weight, but I could not figure out why so I was glad to see other comments on weight gain. I have been diaganosed with high blood pressure, but I do not know if it is related to the shot. I cannot say to the effectiveness because I have to receive the injection for 3 to 5 years. I am crossing my fingers. Read More Read Less

lower abdominal aches after injections for a few days than back to normal was on 1 implant for a while than had to increase to 2 implants to stop my menstrual cycle after about a year had to start back up on the implants because cycles started again now on 3 implants every month for the last 4 months don't know how long I'll be on it this time around. But, as long as it keeps my cancer from returning I'll take it as long as needed.

just started it

After trying for several years to get pregnant my doctor found out I not only had endometrosis but several fib. I have been on lipron to a force menapause and had fib surg. finally I got pregnant but only carried 6wk. last year my endemetrosis and fib came back I have been on zoledex for what is soon to be 6 months. I truely understand the VERY bad HOTFLASHES not to mention the moodswings I am hoping that in a few months to try to get pregnant again..hope is always there..