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How do antihistamines treat motion sickness?

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Antihistamines, both prescription and over-the-counter, are the most widely used medications for motion sickness. Cyclizine (Marezine) and dimenhydrinate (Dramamine) are two major ones.

Make sure to read the drug labels, though. One of the big side effects of these medications is drowsiness. Some products use different ingredients that don’t make you as sleepy, but they may not work as well.

SOURCES:

American Academy of Family Physicians: "Prevention and Treatment of Motion Sickness."

American Academy of Pediatrics: "Car Sickness."

CDC: "Traveler’s Health: Motion Sickness."

Lackner, J. Experimental Brain Research, June 2014.

Mayo Clinic: "Motion Sickness: First Aid."

Mount Sinai Hospital: "Motion Sickness."

University of Maryland Medical Center: "Motion sickness."

Vestibular Disorders Association: "The Human Balance System."

Reviewed by Sabrina Felson on November 7, 2020

SOURCES:

American Academy of Family Physicians: "Prevention and Treatment of Motion Sickness."

American Academy of Pediatrics: "Car Sickness."

CDC: "Traveler’s Health: Motion Sickness."

Lackner, J. Experimental Brain Research, June 2014.

Mayo Clinic: "Motion Sickness: First Aid."

Mount Sinai Hospital: "Motion Sickness."

University of Maryland Medical Center: "Motion sickness."

Vestibular Disorders Association: "The Human Balance System."

Reviewed by Sabrina Felson on November 7, 2020

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