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Nail-Patella Syndrome

Medically Reviewed by Stephanie S. Gardner, MD on April 26, 2022

photo of nail-patella syndrome

Also known as hereditary osteo-onychodysplasia, nail-patella syndrome is a genetic disease that largely affects the development of your finger and toenails but can cause changes in the development of knees, elbows and the pelvis. Nails may be absent or underdeveloped and discolored, split, ridged, or pitted. It is caused by the LMX1B gene. Those with Nail-patella syndrome are also at risk for kidney disease and glaucoma.

Article: Nail Patella Syndrome

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Photo Credit: www.janwijten.com / Wikimedia Commons

Sources: 

National Library of Medicine

National Center for Advancing Translational Sciences – Genetic and Rare Diseases Information Center

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