Goodpasture syndrome is a rare but serious autoimmune disease that attacks the lungs and kidneys.
The disease occurs when the body's immune system mistakenly produces antibodies against collagen in the lungs and kidneys. Collagen is a protein that helps form connective tissue.
Goodpasture syndrome initially causes vague symptoms such as fatigue. But it can rapidly involve the lungs and kidneys. It is almost always fatal if it is not quickly diagnosed and treated.
function is decreased, substances such as
creatinine, and certain
electrolytes begin to build up in the blood. The
following tests measure levels of these substances to show how well your kidneys are working.
A reticulocyte count shows how many red
blood cells are being produced by the bone marrow.
Iron studies show your level of iron, which is needed for
erythropoietin to work the way it should.
A serum ferritin test measures the protein that binds to iron in your body.
Your doctor may use other tests to
monitor kidney function or to find out whether another kidney disease
or condition is contributing to reduced kidney function.
ultrasound of the kidney (renal ultrasound) helps estimate how long you may have had chronic
kidney disease. It also checks whether urine flow from the
kidneys is blocked. An ultrasound also may help find causes
of kidney disease, such as obstruction or
polycystic kidney disease.
kidney biopsy may help find out the cause of chronic
kidney disease. After a kidney transplant, a doctor may use this test if he or she suspects the organ is being rejected by your body.
Early screening for chronic kidney disease
recommend screening tests for chronic kidney disease in high-risk groups, such
as people with
high blood pressure. Kidney disease runs in families, so close
family members may also want to have their kidney function tested. Being diagnosed with kidney
disease before it has progressed gives you the best chance to control the
To learn more about screening if you already have diabetes or high blood pressure, see: