Acute tubular necrosis
(ATN) is a condition in which the small filtering tubes in the kidney are
injured. ATN is a common cause of intrinsic acute renal failure often seen in
people who are already hospitalized. ATN may occur because of:
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Decreased blood flow in the kidneys. Decreased
blood flow may be caused by:
Surgery, especially cardiovascular or
Direct injury to the kidney.
Severe muscle injury or extreme physical exertion.
Substances, such as
medicines that are toxic to the kidneys. Many
substances that are not toxic to the kidneys in a healthy person may become
toxic in a person who has existing kidney problems or another condition that
increases his or her risk of acute renal failure, such as heart failure,
diabetes, or multiple myeloma.
Acute glomerulonephritis (AGN)
a condition in which the tiny blood vessels in the kidneys become inflamed and
damaged. Damaged glomeruli do not filter blood properly.
glomerulonephritis may be caused by an abnormal
immune system response. Some specific conditions that
cause acute glomerulonephritis include: