In Alzheimer’s disease, nerve cells in the brain die gradually. This makes it increasingly difficult for your brain’s signals to be sent properly.
Alzheimer’s disease symptoms may be hard to recognize at first. You may assume that symptoms such as mild forgetfulness or an occasional loss of focus are normal signs of aging. But as the disease progresses, Alzheimer’s disease symptoms become more than “normal” changes. They become frightening, incapacitating, and dangerous. In the latter stages of disease, people with Alzheimer’s often require round-the-clock care.
Sundowning, or sundown syndrome, affects some people who have Alzheimer's disease and dementia. People with dementia who "sundown" get confused and agitated as the sun goes down -- and sometimes through the night.
Sundowning may prevent people with dementia from sleeping well. It may also make them more likely to wander. Due to the stress it puts on caregivers, sundowning is a common cause of caregiver burnout.