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Alzheimer's Disease Health Center

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Overeating May Raise Risk for Memory Problems

Study: Eating More Than 2,100 Calories a Day May Place Seniors at Higher Risk
WebMD Health News
Reviewed by Louise Chang, MD

Feb. 12, 2012 -- Overeating may double your risk of developing memory problems.

Older adults who ate between 2,100 and 6,000 calories each day were twice as likely to develop memory problems. The new findings are slated to be presented at the annual meeting of the American Academy of Neurology in New Orleans.

The more calories the adults took in, the higher their risk for mild cognitive impairment (MCI), which is the medical term for mild memory loss. While not serious enough to seriously interfere in their daily lives, people with MCI may have problems remembering recent events and/or new information, as well as have issues with other brain functions. People with MCI are at greater risk for developing dementia, but not all do.

The study involved more than 1,200 people between the ages of 70 and 89, including 163 who had signs of MCI. Participants described their diet during the preceding year in a food questionnaire.

One-third ate between 600 and 1,526 calories per day, one-third ate between 1,526 and 2,143, and one-third ate between 2,143 and 6,000 calories per day, the study shows. The results took into account other factors such as age, sex, education level, history of stroke, and depression.

Risk Increases With Calories

Those who took in the highest number of calories per day had double the risk for MCI.

“This fits into what we know about midlife risk factors for Alzheimer's disease,” says Sam Gandy, MD, PhD, in an email. He is the associate director of the Mount Sinai Alzheimer's Disease Research Center in New York. “We know that obesity increases risk for Alzheimer's, and we know that caloric restriction decreases risk for Alzheimer's, so the overeating story fits well."

David Loewenstein, PhD, agrees. “More and more research has shown that anything that is good for the heart is good for the brain, and when people overeat, there are complications including risk for diabetes, stroke, and memory problems.” He is a professor of psychiatry and behavioral sciences at the University of Miami Miller School of Medicine.

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