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    Some of World's Tiniest Preemies Are Growing Up Healthy

    Two of the Smallest Surviving Infants Develop Normally, but Height and Weight Lag a Bit
    By Cari Nierenberg
    WebMD Health News
    Reviewed by Laura J. Martin, MD

    World's tiniest preemie at birth and at 22Dec. 12, 2011 -- Against heavy odds, the world's tiniest and the fourth-smallest surviving infants have had normal childhood development, a new study shows, although the girls’ heights and weights still lag behind other kids the same age.

    Little information is available to doctors and parents on how extremely low-birth-weight babies develop and grow as toddlers, school-age children, or into young adulthood. So a report like this offers a rare glimpse at the long-term health and growth of two of the world's teeniest premature babies as they get older.

    Rumaisa Rahman, a girl who holds the Guinness Book of World Records title of "World's Smallest Surviving Baby," is at her five-year follow-up doctor's visit.

    Born at just 26 weeks after her mother had severe preeclampsia, a serious condition involving high blood pressure and other abnormalities during pregnancy, Rumaisa was a twin. She weighed 9.2 ounces. She was roughly 9 inches long. Rumaisa spent 142 days in the hospital's neonatal intensive care unit.

    Madeline Mann is now a 22-year-old college senior. She was born at nearly 27 weeks into the pregnancy, also to a mother who had preeclampsia. She weighed roughly 9.9 ounces and was also about 9 inches long. Madeline was hospitalized for 122 days as a newborn before going home.

    Her case is the first 20-year follow-up for one of the world's smallest surviving infants reported in the medical literature.

    Few babies born at birth weights of less than 14 ounces survive, so cases such as these are very rare. But the numbers of these "micro-preemies" who survive are on the rise.

    The research appears in the Dec. 12 issue of Pediatrics.

    Not Typical Outcomes

    Both girls, who were born at the same Illinois hospital, showed normal language skills and hit normal milestones for walking and toilet training. Rumaisa's movement skills -- writing, grasping for toys, and getting dressed -- are mildly delayed, while Madeline's are described as normal.

    Both girls remain small for their age for weight and height. Rumaisa is in first grade with an individualized education plan.

    At 20, Madeline stood 4 feet, 7 inches and weighed about 65 pounds. Her growth has been consistently far below other girls her age.

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