Brain & Nervous System Health Center
Neutropenia, General
Important
It is possible that the main title of the report Neutropenia, General is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Synonyms
- Neutropenia, Autoimmune
Disorder Subdivisions
- Neutropenia, Chronic Congenital
- Neutropenia, Chronic Idiopathic
- Neutropenia, Cyclic
General Discussion
Severe chronic neutropenia (SCN) is a rare blood disorder characterized by abnormally low levels of certain white blood cells (neutrophils) in the body (neutropenia). Neutrophils play an essential role in fighting bacterial infections by surrounding and destroying invading bacteria (phagocytosis). Symptoms associated with severe chronic neutropenia include recurring fevers, mouth sores (ulcers), and/or inflammation of the tissues that surround and support the teeth (periodontitis). Due to low levels of neutrophils, affected individuals may be more susceptible to recurring infections that, in some cases, may result in life-threatening complications. SCN may last for months or years and can affect both children and adults. Clinicians recognize four forms of the disorder: congenital, cyclical, idiopathic, and autoimmune neutropenia. The term idiopathic is used when severe chronic neutropenia occurs for unknown reasons.
Resources
National Neutropenia Network
PO Box 1693
Brighton, MI 48116
USA
Tel: (810)229-5797
Email: leereeves99@gmail.com
Internet: http://www.neutropenianet.org
Severe Chronic Neutropenia International Registry
Plaza 600 Building
600 Stewart Street
Suite 1503
Seattle, WA 98101
USA
Tel: (206)543-9749
Fax: (206)543-3668
Tel: (800)726-4463
Email: Registry@u.washington.edu
Internet: http://www.depts.washington.edu/registry/
NIH/National Heart, Lung and Blood Institute Information Center
P.O. Box 30105
Bethesda, MD 20824-0105
Tel: (301)592-8573
Fax: (301)251-1223
Email: nhlbiinfo@rover.nhlbi.nih.gov
Neutropenia Support Association, Inc.
971 Corydon Avenue
Winnepeg
Manitoba, R3M 3S7
Canada
Tel: 2044898454
Tel: 8006638876
Email: stevensl@neutropenia.ca
Internet: http://www.neutropenia.ca
Severe Chronic Neutropenia International Registry Australia
2nd Floor Marian House
St. John of God Hospital
1002 Mair Street
Ballarat, 3350
AUSTRALIA
Tel: 61-3-5333 4811
Fax: 61-3-5333 4813
Email: scnirau@ballarat.edu.au
Internet: http://www.freyja.ballarat.edu.au:8080/~scnirau/
MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
150 Custer Court
Green Bay, WI 54301-1243
USA
Tel: (920)336-5333
Fax: (920)339-0995
Tel: (877)336-5333
Email: mums@netnet.net
Internet: http://www.netnet.net/mums/
For a Complete Report:
This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org
Last Updated: 5/5/2009
Copyright 1991, 1997, 1998, 2006, 2007, 2009 National Organization for Rare Disorders, Inc.
WebMD Medical Reference from the National Organization of Rare Disorders
Important Safety Information
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