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Brain & Nervous System Health Center

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Power of Thought Could Help Paralyzed Move

WebMD Health News

Nov. 15, 2000 -- It sounds like science fiction, but people who are paralyzed may one day be able to control artificial limbs by essentially willing them to move, and those isolated by motor diseases like muscular sclerosis may be able to move and communicate through thought.

A primate study released Wednesday suggests it is possible, and researchers say human trials could begin in as little as a decade.

Duke University Medical Center scientists implanted electrodes in the brains of two owl monkeys that enabled the animals to use brain signals to control a robot arm. The brain signals were even transmitted over the Internet, remotely controlling a robot arm 600 miles away at the Massachusetts Institute of Technology in Boston. Findings from the studies were reported in the Nov. 16, 2000 issue of Nature.

Researchers say their computerized system could be an important step toward what they call a "brain-machine interface," that would allow paralyzed patients to control prosthetic limbs. Their research could also provide a clearer understanding of how the brain works.

"The goal of using signals from the brain to drive artificial limbs has been studied for 30 years," Sandro Mussa-Ivaldi, PhD, of Northwestern University in Evanston, Ill. tells WebMD. "Technologically, this is a significant advance, but there is still a long way to go." Mussa-Ivaldi was not involved with the study, but wrote an editorial accompanying it.

"[The study] provides a simple solution to the problem of extracting movement information from neural signals detected by microelectrodes implanted in different regions of the [brain] of living owl monkeys," Mussa-Ivaldi writes.

Neurons are the billions of nerve cells that transmit electrical impulses throughout the nervous system, allowing a person to do everything from scratching an itch to conducting a symphony.

"There are up to 10 billion neurons in the brain," MIT researcher Mandayam Srinivasan, PhD tells WebMD. "When you perform a simple action like moving your arm, literally thousands if not millions of neurons are involved. What we have done in this study is sampled about 100 of those neurons. That doesn't sound like much, but it is a big step compared to what we were able to do just a few years ago."

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