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Brain & Nervous System Health Center

Dental X-rays Linked to Brain Tumors

Annual X-rays May Expose Patients to Unnecessary Risk
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WebMD Health News
Reviewed by Louise Chang, MD

April 10, 2012 -- Getting frequent dental X-rays appears to increase the risk for a commonly diagnosed brain tumor, a new study finds.

Exposure to ionizing radiation -- the kind found in X-rays -- is the biggest known environmental risk factor for largely non-malignant meningioma brain tumors. Routine dental X-rays are among the most common sources of radiation for most healthy people in the U.S.

The new study suggests that performing frequent X-rays may expose patients to unnecessary risk.

"These findings should not prevent anyone from going to the dentist," says lead researcher and neurosurgeon Elizabeth B. Claus, MD, PhD, of Yale University School of Medicine and Boston's Brigham and Women's Hospital. "But it appears that a large percentage of patients receive annual X-rays instead of every two to three years, which is the recommendation for healthy adults."

Dental X-ray, Benign Brain Tumors

While the vast majority of meningiomas are non-malignant, they often grow to be very large and can cause a wide range of potentially serious symptoms, including vision and hearing loss, frequent headaches, memory loss, and even seizures.

They are the most frequently diagnosed brain tumors among adults in the United States, accounting for about a third of all primary brain and central nervous system tumors.

Several small studies have suggested a link between cumulative dental X-ray exposures and meningiomas, but the findings were inconclusive.

In the newly published study -- the largest ever to examine the question -- people who reported having "bitewing" X-rays at least yearly were found to have a 40% to 90% greater risk of meningioma.

The study shows an association but does not prove a cause-effect relationship.

The study included about 1,400 meningioma patients between the ages of 20 and 79 when they were diagnosed between the spring of 2006 and the spring of 2011.

When the patients' self-reported dental histories were compared to adults with similar characteristics who did not have the brain tumors, lifetime exposure to either bitewing or panoramic dental X-rays -- which include the upper and lower jaw -- was significantly associated with meningioma risk. This risk was higher in people who received panoramic X-rays when they were younger than 10.

The meningioma patients were more than twice as likely as the adults without brain tumors to have had dental X-rays at some point during their lives, Claus tells WebMD.

The study appears in the April 10 issue of the American Cancer Association journal Cancer.

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