Breast Cancer Health Center
Breast Cancer in Men
How Can Men Get Breast Cancer?
Even though men do not have breasts like women, they do have a small amount of breast tissue. In fact the "breasts" of an adult man are similar to the breasts of a girl before puberty, and consist of a few ducts surrounded by breast and other tissue. In girls, this tissue grows and develops in response to female hormones, but in men -- who do not secrete the same amounts of these hormones -- this tissue does not develop.
However, because it is still breast tissue, men can develop breast cancer. In fact, men get the same types of breast cancers that women do, although cancers involving the milk producing and storing regions of the breast are very rare. According to the American Cancer Society, an estimated 2,300 cases of breast cancer will be diagnosed in men in 2009.
Why Do I Not Hear About Breast Cancer In Men As Much As I Hear About Breast Cancer In Women?
Breast cancer in men is a very rare disease. This is possibly due to their smaller amount of breast tissue and the fact that men produce smaller amounts of hormones like estrogen that are known to affect breast cancers in women.
In fact, only about 1 in 100 breast cancers affect men and only about 10 men in a million will develop breast cancer.
Which Men Are More Likely to Get Breast Cancer?
It is very rare for a man under age 35 to get breast cancer, but the likelihood of developing the disease increases with age, with most being detected between the ages of 60 to 70 years. Family history of breast cancer in a close female relative and a history of radiation exposure of the chest can also increase the risk.
The clearest risk for developing breast cancer seems to be in men who have had an abnormal enlargement of their breasts (called gynecomastia) in response to drug or hormone treatments, or even some infections and poisons. Individuals with a rare genetic disease called Klinefelter's syndrome, who often have gynecomastia as part of the syndrome, are especially prone to develop breast cancer. Men with severe liver disease tend to have lower levels of male hormones (androgens) and higher levels of female hormones (estrogens) putting them at an increased risk of developing gynecomastia and breast cancer. Also, diseases of the testicles such as mumps orchites, a testicular injury, or an undescended testicle increase the risk of male breast cancer.
How Serious Is Breast Cancer in Men?
Doctors used to think that breast cancer in men was a more severe disease than it was in women, but it now seems that for comparably advanced breast cancers, men and women have similar outcomes.
The major problem is that breast cancer in men is often diagnosed later than breast cancer in women. This may be because men are less likely to be suspicious of an abnormality in that area. In addition, their small amount of breast tissue is harder to feel -- making it more difficult to catch these cancers early, and allowing tumors to spread more quickly to the surrounding tissues.
WebMD Medical Reference
VIVELLE-DOT (estradiol transdermal system) IS AVAILABLE BY PRESCRPTION ONLY.
INDICATION
Vivelle-Dot is used after menopause to: reduce moderate to severe hot flashes; treat moderate to severe dryness, itching and burning in or around the vagina; help reduce your chances of getting osteoporosis (thin weak bones); and treat certain conditions in which a young woman's ovaries do not produce enough estrogens naturally. Vivelle-Dot 0.025 mg/day is only used to prevent osteoporosis from menopause. If you use Vivelle-Dot only to treat your dryness, itching, and burning in and around your vagina or if you use Vivelle-Dot only to prevent osteoporosis from menopause, talk with your healthcare professional about whether a different treatment or medicine without estrogens might be better for you.
IMPORTANT SAFETY INFORMATION
Estrogens increase the chances of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are taking estrogens. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb).
Do not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes. Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer, and blood clots. Using estrogens with progestins may increase your risk of dementia (decline in memory and thinking skills).
Vivelle-Dot should not be used if you have unusual vaginal bleeding; currently have or have had certain cancers, including cancer of the breast or uterus; had a stroke or heart attack in the recent past (for example, in the past year); currently have or have had blood clots; currently have or have had liver problems; or think you may be, or know that you are, pregnant.
The most common side effects that may occur with Vivelle-Dot are headache, breast tenderness, and back pain.
You and your healthcare professional should talk regularly about whether you still need treatment with Vivelle-Dot.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see Full Prescribing Information for Vivelle-Dot.

