Genetic Changes Influence Breast Cancer Development and Survival
Women who have the genetic mutation called BRCA are more likely to develop
breast cancer before age 50, start treatment with more advanced disease, have
lymph node involvement, experience tumor recurrence, and have shorter
The presence of the mutation alone does not predict survival and should not
affect treatment decisions following surgery.
A researcher suggests that women who have BRCA mutations undergo advanced
surveillance starting at age 25, with self-breast exams each month, breast
exams by a profession three to four times per year, and mammography.