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Genetic Changes Influence Breast Cancer Development and Survival

Vital Information:

  • Women who have the genetic mutation called BRCA are more likely to develop breast cancer before age 50, start treatment with more advanced disease, have lymph node involvement, experience tumor recurrence, and have shorter survival.
  • The presence of the mutation alone does not predict survival and should not affect treatment decisions following surgery.
  • A researcher suggests that women who have BRCA mutations undergo advanced surveillance starting at age 25, with self-breast exams each month, breast exams by a profession three to four times per year, and mammography.
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