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Antiperspirant: Link to Breast Cancer?

There's Much Debate, but Association May Be Just an Urban Myth
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WebMD Health News
Reviewed by Louise Chang, MD

Feb. 28, 2006 -- Does regular use of antiperspirants increase a woman's risk for developing breast cancer? A researcher in the U.K. says the answer could very well be yes, but experts tell WebMD that there is still little evidence to back up the claim.

The antiperspirant-breast cancer claim has achieved something akin to urban legend status on the Internet and in the popular press, despite that fact that few clinical studies in humans have addressed the issue.

One of the strongest, published in 2002, found no link between antiperspirant or deodorant use and breast cancer risk. Researchers compared usage patterns among roughly 800 breast cancer patients and a similar number of women without the disease.

Easing Women's Fears

Biostatistician Dana Mirick, MS, who led the study, says the findings should ease women's fears.

"I think that the people who do this type of research consider the matter closed," she tells WebMD.

But cancer researcher Philippa Darbre, PhD, of the University of Reading in England, sees it differently. She says the evidence is mounting that the aluminum-based active ingredient in antiperspirants can mimic estrogen in the body.

"Lifetime exposure to estrogen is the risk factor which is tied most strongly to breast cancer," Darbre tells WebMD. "If the aluminum salts in antiperspirants enter the body and mimic estrogen it stands to reason that constant exposure over many years may pose a risk."

Risks of Aluminum Exposure?

Aluminum salts are the active ingredient in the vast majority of antiperspirants, and antiperspirants are a major source of exposure to aluminum in humans.

Products labeled as deodorants alone may not have aluminum, but the vast majority of commercially available antiperspirants do contain aluminum salts. They make up as much as a quarter of the volume of some antiperspirants.

Darbre says her own cellular research shows that aluminum salt exposure can influence estrogen activity. Because antiperspirants are used so closely to the breast, and are often used by women directly after shaving -- which might allow for easier absorption -- she says it is reasonable to question whether antiperspirant exposure could influence breast cancer risk.

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