Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Breast Cancer Health Center

Font Size

Can Breast Cancer Disappear?

Study Shows Some Cancers Detected by Mammograms Regress on Their Own; American Cancer Society Disagrees

Breast Cancer Screening continued...

He says the results imply that as many as two out of three screenings detected lesions -- including invasive cancers and the noninvasive ductal carcinoma in situ (DCIS) -- may be pseudo cancers.

Maehlen expects the conclusion to spark debate. "The majority of the people in the field would be skeptical," he says.

As to which women might be more likely to have breast cancers that spontaneously regress, Maehlen says that is not known. "It could be the immune system is the cause for the disappearance of some cancers," he says, presumably with the healthiest immune systems most likely to fight off cancers.

Or, he says, it could depend on the biology of the individual cancer as to whether it regresses.

Second Opinions

The American Cancer Society took issue with the thinking that cancer may regress on its own. "The conclusion that more than 1 in 5 invasive breast cancers is destined to regress without incident if not detected by mammography [the 22% figure cited in the study] is nothing more than an overreaching leap in logic," Robert A. Smith, PhD, director of cancer screening for the American Cancer Society, says in a prepared statement.

Other studies have found that "overdiagnosis" -- not the same as regression -- probably occurs in less than 5% of all screen-detected cancer cases if it exists at all, Smith says.

He says the benefits of regular mammograms far outweigh any limitations, such as false-positive results and "possibly a small rate of overdiagnosis."

The study has weaknesses, but also strengths, says Robert Kaplan, PhD, the Wasserman Distinguished Professor and chair of the department of health services at the University of California, Los Angeles School of Public Health, in an editorial accompanying the study.

As a result, he writes, "the findings should not be dismissed."

The study, Kaplan says, points out how little experts know about the natural history of breast cancer.

The concept of breast cancer spontaneously regressing is worth further study, Kaplan writes.

1 | 2

Today on WebMD

Breast Cancer Overview
From self-exams and biopsies to reconstruction, we’ve got you covered.
Dealing with breast cancer
Get answers to your questions.
woman having mammogram
Experts don’t agree on all fronts, but you can be your own advocate.
woman undergoing breast cancer test
Many women worry. But the truth? Most abnormalities aren’t breast cancer.
Breast Cancer Treatments Improving
Resolved To Quit Smoking
Woman getting mammogram
Screening Tests for Women
ovarian cancer overview slideshow
serious woman
what is your cancer risk
10 Ways to Revitalize Slideshow