Breast Cancer - Medications
Medicines are used to treat breast cancer and also to help relieve side effects of treatment.
of medicines is typically used to treat breast cancer. The number of
cycles of treatment will depend on the medicines that are used and how the
medicines are given. Chemotherapy often uses several medicines together. Some of the most commonly used medicines
- Breast Cancer: Should I Have Chemotherapy for Early-Stage Breast Cancer?
side effects of chemotherapy depend mainly on the medicines you receive. As
with other types of treatment, side effects vary from person to person. Your doctor may also prescribe medicines to control and prevent nausea and vomiting.
Medicines used for hormone therapy stop or slow the growth of hormone-sensitive cancer cells. These medicines include:
- Selective estrogen receptor modulators (SERMs), such as raloxifene (Evista), tamoxifen (Nolvadex), and toremifene (Fareston).
- Antiestrogen medicine, such as fulvestrant (Faslodex).
- Aromatase inhibitors, such as anastrozole (Arimidex), exemestane (Aromasin), and letrozole (Femara).
- LH-RH agonists, such as goserelin (Zoladex) and leuprolide (Lupron).
Hormone-blocking treatments may cause fewer side effects than chemotherapy. If you are deciding
what type of medicine to use, weigh the benefits and risks of these medicines for your type of cancer.
Targeted therapies use medicines or substances that go directly to the cancer cells and don't harm normal cells. They include
monoclonal antibodies, tyrosine kinase inhibitors, and PARP inhibitors.
- Trastuzumab (Herceptin) and pertuzumab (Perjeta) are used to treat HER-2 positive breast cancer. These medicines are monoclonal antibodies. They help chemotherapy work better.
- Lapatinib, a tyrosine kinase inhibitor, may be used to treat women who have HER-2+ cancer that has progressed even after they have taken trastuzumab.
- PARP inhibitor therapy is another kind of targeted therapy for triple-negative breast cancer (cancer cells that do not have estrogen or progesterone receptors or large amounts of HER-2).
The side effects of targeted therapies will depend on the type of medicine that is given. They include nausea, vomiting, and diarrhea. Some medicines can also cause side effects that are more serious.