A meningioma is a tumor that forms on membranes that cover the brain and spinal cord just inside the skull.
Specifically, the tumor forms on the three layers of membranes that are called meninges.
These tumors are often slow-growing. As many as 90% are benign (not cancerous).
Most meningiomas occur in the brain. But they can also grow on parts of the spinal cord.
Often, meningiomas cause no symptoms and require no immediate treatment. But the growth of benign meningiomas can cause serious problems...
Updated statistics with estimated new cases and deaths for 2014 (cited American Cancer Society as reference 1).
Treatment Option Overview
Added text to state that the natural histories of these tumors are variable, depending on histological and molecular factors; therefore, treatment guidelines are evolving. Also revised text to state that therapy involving surgically implanted carmustine-impregnated polymer wafers combined with postoperative external-beam radiation therapy may play a role in the treatment of high-grade gliomas (grade III and IV gliomas) in some patients.
Management of Specific Tumor Types and Locations
Revised the Glioblastomas subsection extensively.
Revised text to state that patients who have oligodendrogliomas (WHO grade II) generally have a better prognoses than do patients who have diffuse astrocytomas; however, most of the oligodendrogliomas eventually progress.
Added text to include stereotactic radiosurgery for tumors less than 3 cm as a standard treatment option for grade 1 meningiomas and revised a treatment option to read fractionated radiation therapy for patients with resectable tumors.
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