Understanding Cervical Cancer -- the Basics
Learn the basics about cervical cancer and what causes it from WebMD.
WebMD explains the causes, symptoms, and treatment of cervical dysplasia, a precancerous condition in which abnormal cells are found on or around the cervix.
WebMD provides an overview of cervical cancer, including causes, symptoms, diagnosis, treatment, and prevention.
Cervical Cancer Clinical Trials
Here are resources for women interested in participating in a clinical trial for cervical cancer.
Cervical Cancer Screening (PDQ®): Screening - Patient Information [NCI] - Get More Information From NCI
Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support
Cervical Cancer Screening (PDQ®): Screening - Patient Information [NCI] - General Information About Cervical Cancer
WebMD explains the types of cervical cancer and the prognosis when you're diagnosed in different stages.
Uterine Sarcoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Treatment Options for Recurrent Cervical Cancer
Treatment of recurrent cervical cancer may include the following:Pelvic exenteration followed by radiation therapy combined with chemotherapy.Chemotherapy as palliative therapy to relieve symptoms caused by the cancer and improve quality of life.Clinical trials of new anticancer drugs or drug combinations.Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with recurrent cervical cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
Endometrial Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - General Information About Endometrial Cancer
Endometrial cancer is a disease in which malignant (cancer) cells form in the tissues of the endometrium. The endometrium is the lining of the uterus,a hollow,muscular organ in a woman’s pelvis. The uterus is where a fetus grows. In most nonpregnant women,the uterus is about 3 inches long. The lower,narrow end of the uterus is the cervix,which leads to the vagina. Cancer of the ...
Uterine Sarcoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Recurrent Cervical Cancer Treatment
The size of the primary tumor is an important prognostic factor and should be carefully evaluated in choosing optimal therapy. Patterns-of-care studies in stage IIIA/IIIB patients indicate that survival is dependent on the extent of the disease, with unilateral pelvic wall involvement predicting a better outcome than bilateral involvement, which in turn predicts a better outcome than involvement of the lower third of the vaginal wall. These studies also reveal a progressive increase in local control and survival paralleling a progressive increase in paracentral (point A) dose and use of intracavitary treatment. The highest rate of central control was seen with paracentral (point A) doses of more than 85 Gy. Patients who are surgically staged as part of a clinical trial and are found to have small volume para-aortic nodal disease and controllable pelvic disease may be cured with external-beam pelvic and para-aortic radiation therapy. If postoperative external-beam radiation
Uterine Sarcoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Treatment Option Overview for Cervical Cancer
Standard treatments for patients with cervical cancer include:Surgery.Radiation therapy.Chemotherapy.Five randomized, phase III trials (GOG-85, RTOG-9001, GOG-120, GOG-123, and SWOG-8797) have shown an overall survival advantage for cisplatin-based therapy given concurrently with radiation therapy,[1,2,3,4,5,6] while one trial examining this regimen demonstrated no benefit. The patient populations in these studies included women with Féderation Internationale de Gynécologie et d'Obstétrique (FIGO) stages IB2 to IVA cervical cancer treated with primary radiation therapy and women with FIGO stages I to IIA disease found to have poor prognostic factors (metastatic disease in pelvic lymph nodes, parametrial disease, or positive surgical margins) at the time of primary surgery. Although the positive trials vary in terms of the stage of disease, dose of radiation, and schedule of cisplatin and radiation, the trials demonstrate significant survival benefit for this combined approach.