Cervical Cancer Screening (PDQ®): Screening - Patient Information [NCI] - Changes to This Summary (12 / 02 / 2013)
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above. Editorial changes were made to this summary.
Cervical Cancer Prevention (PDQ®): Prevention - Patient Information [NCI] - General Information About Endometrial Cancer
Related Summaries Note: Other PDQ summaries containing information related to endometrial (uterine corpus) cancer include the following: Uterine Sarcoma Treatment Endometrial Cancer Screening Endometrial Cancer Prevention Statistics Note: Estimated new cases and deaths from endometrial (uterine corpus) cancer in the United States in 2010:[ 1 ] New cases: 43,470. Deaths: 7,950. Cancer of the ...
Cervical Cancer Screening (PDQ®): Screening - Patient Information [NCI] - Recurrent Endometrial Cancer
Recurrent endometrial cancer is cancer that has recurred (come back) after it has been treated. The cancer may come back in the uterus, the pelvis, in lymph nodes in the abdomen, or in other parts of the body.
Gestational Trophoblastic Disease Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Treatment Options for Gestational Trophoblastic Disease
A link to a list of current clinical trials is included for each treatment section. For some types of gestational trophoblastic disease, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.Hydatidiform MolesTreatment of a hydatidiform mole may include the following:Surgery (Dilatation and curettage with suction evacuation) to remove the tumor.After surgery, beta human chorionic gonadotropin (β-hCG) blood tests are done every week until the β-hCG level returns to normal. Patients also have follow-up doctor visits monthly for up to 6 months. If the level of β-hCG does not return to normal or increases, it may mean the hydatidiform mole was not completely removed and it has become cancer. Pregnancy causes β-hCG levels to increase, so your doctor will ask you not to become pregnant until follow-up is finished.For disease that remains after surgery, treatment is usually chemotherapy.Check for U.S. clinical
Gestational Trophoblastic Disease Treatment (PDQ®): Treatment - Patient Information [NCI] - General Information About Gestational Trophoblastic Disease
Gestational trophoblastic disease (GTD) is a broad term encompassing both benign and malignant growths arising from products of conception in the uterus. GTD may be classified as follows:Hydatidiform mole (HM).Complete HM.Partial HM.Gestational trophoblastic neoplasia.Invasive mole.Choriocarcinoma.Placental-site trophoblastic tumor (very rare).Epithelioid trophoblastic tumor (even more rare).The reported incidence of GTD varies widely worldwide, from a low of 23 per 100,000 pregnancies (Paraguay) to a high of 1,299 per 100,000 pregnancies (Indonesia). However, at least part of this variability is caused by differences in diagnostic criteria and reporting. The reported incidence in the United States is about 110 to 120 per 100,000 pregnancies. The reported incidence of choriocarcinoma, the most aggressive form of GTD, in the United States is about 2 to 7 per 100,000 pregnancies. The U.S. age-standardized (1960 World Population Standard) incidence rate of choriocarcinoma is
Endometrial Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - General Information About Endometrial Cancer
Endometrial cancer is a disease in which malignant (cancer) cells form in the tissues of the endometrium. The endometrium is the lining of the uterus,a hollow,muscular organ in a woman’s pelvis. The uterus is where a fetus grows. In most nonpregnant women,the uterus is about 3 inches long. The lower,narrow end of the uterus is the cervix,which leads to the vagina. Cancer of the ...
Cervical Cancer Screening (PDQ®): Screening - Patient Information [NCI] - Stages of Endometrial Cancer
After endometrial cancer has been diagnosed, tests are done to find out if cancer cells have spread within the uterus or to other parts of the body.The process used to find out whether the cancer has spread within the uterus or to other parts of the body is called staging. The information gathered from the staging process determines the stage of the disease. It is important to know the stage in order to plan treatment. Certain tests and procedures are used in the staging process. A hysterectomy (an operation in which the uterus is removed) will usually be done to help find out how far the cancer has spread.The following procedures may be used in the staging process: Pelvic exam: An exam of the vagina, cervix, uterus, fallopian tubes, ovaries, and rectum. The doctor or nurse inserts one or two lubricated, gloved fingers of one hand into the vagina and the other hand is placed over the lower abdomen to feel the size, shape, and position of the uterus and ovaries. A speculum is also
Endometrial Cancer Screening (PDQ®): Screening - Health Professional Information [NCI] - Low-Risk Gestational Trophoblastic Neoplasia (FIGO Score 0–6) Treatment
There is no consensus on the best chemotherapy regimen for initial management of low-risk gestational trophoblastic neoplasia (GTN), and first-line regimens vary by geography and institutional preference. Most regimens have not been compared head-to-head, and the level of evidence for efficacy is often limited to 3iiDii except as noted below. Even if there are differences in initial remission rate among the regimens, salvage with alternate regimens is very effective, and the ultimate cure rates are generally 99% or more. The initial regimen is generally given until a normal beta human chorionic gonadotropin (beta-hCG) (for the institution) is achieved and sustained for 3 consecutive weeks (or at least for one treatment cycle beyond normalization of the beta-hCG). A salvage regimen is instituted if any of the following occur:A plateau of the beta-hCG for 3 weeks (defined as a beta-hCG decrease of 10% or less for 3 consecutive weeks).A rise in beta-hCG of greater than 20%
Cervical Cancer Screening (PDQ®): Screening - Patient Information [NCI] - Cellular Classification of Cervical Cancer
Squamous cell (epidermoid) carcinoma comprises approximately 90%, and adenocarcinoma comprises approximately 10% of cervical cancers. Adenosquamous and small cell carcinomas are relatively rare. Primary sarcomas of the cervix have been described occasionally, and malignant lymphomas of the cervix, primary and secondary, have also been reported.
Cervical Cancer Screening (PDQ®): Screening - Patient Information [NCI] - Summary of Evidence
Separate PDQ summaries on Prevention of Endometrial Cancer; Endometrial Cancer Treatment; and Uterine Sarcoma Treatment are also available. Benefits There is inadequate evidence that screening by ultrasonography (e.g.,transvaginal ultrasound [TVU]) or endometrial sampling would reduce the mortality from endometrial cancer. Description of the Evidence STUDY DESIGN: No studies have adequately ...