How PMBL Gene Therapy Targets Cancerous Cells
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Primary mediastinal B-cell lymphoma, or PMBL, is a rare type of fast-growing blood cancer. PMBL is a type of non-Hodgkin's lymphoma that starts in your thymus, an organ that makes immune cells.
PMBL happens when your B-cells, a type of white blood cell, grow and multiply out of control. These cancerous B-cells, called lymphocytes, build up in the center of your chest and form tumors.
CAR T-cell therapy, a type of gene therapy, works by using your immune system to fight the lymphoma. Genes have your DNA, the code that tells your cells what to do. Genes that don't work the way they should can cause diseases.
First, your doctor collects some of your T cells and changes their genetic code by putting in a new gene. When your T cells are put back inside your body, they're now programmed to target and kill cancerous lymphocytes.
PMBL happens when your B-cells, a type of white blood cell, grow and multiply out of control. These cancerous B-cells, called lymphocytes, build up in the center of your chest and form tumors.
CAR T-cell therapy, a type of gene therapy, works by using your immune system to fight the lymphoma. Genes have your DNA, the code that tells your cells what to do. Genes that don't work the way they should can cause diseases.
First, your doctor collects some of your T cells and changes their genetic code by putting in a new gene. When your T cells are put back inside your body, they're now programmed to target and kill cancerous lymphocytes.
