Ewing Sarcoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Ewing Sarcoma: Localized Tumors
Standard Treatment OptionsBecause most patients with apparently localized disease at diagnosis have occult metastatic disease, multidrug chemotherapy as well as local disease control with surgery and/or radiation is indicated in the treatment of all patients.[1,2,3,4,5,6,7,8] Current regimens for the treatment of localized Ewing sarcoma achieve event-free survival (EFS) and overall survival (OS) of approximately 70% at 5 years after diagnosis.Current standard chemotherapy in the United States includes vincristine, doxorubicin, and cyclophosphamide, also known as VAdriaC or VDC, alternating with ifosfamide and etoposide (IE). The combination of IE has shown activity in Ewing sarcoma, and a large randomized clinical trial and a nonrandomized trial demonstrated that outcome was improved when IE was alternated with VAdriaC.[2,9,10] Dactinomycin is no longer used in the United States but continues to be used in the Euro-Ewing studies. Increased dose intensity of doxorubicin during
Pruritus (PDQ®): Supportive care - Patient Information [NCI] - About PDQ
PDQ IS A COMPREHENSIVE CANCER DATABASE AVAILABLE ON NCI'S WEB SITE. PDQ is the National Cancer Institute's (NCI's) comprehensive cancer information database. Most of the information contained in PDQ is available online at NCI's Web site. PDQ is provided as a service of the NCI. The NCI is part of the National Institutes of Health,the federal government's focal point for biomedical research. ...
Delirium (PDQ®): Supportive care - Patient Information [NCI] - Effects of Delirium on the Patient, Family, and Health Care Providers
Delirium causes changes in the patient that can upset the family and caregivers.Delirium may be dangerous to the patient if his or her judgment is affected. Delirium can cause the patient to behave in unusual ways. Even a quiet or calm patient can have a sudden change in mood or become agitated and need more care. Delirium can be upsetting to the family and caregivers. When the patient becomes agitated, family members often think the patient is in pain, but this may not be the case. Learning about differences between the symptoms of delirium and pain may help the family and caregivers understand how much pain medicine is needed. Health care providers can help the family and caregivers learn about these differences.Delirium may affect physical health and communication. Patients with delirium are: More likely to fall.Sometimes unable to control bladder and/or bowels.More likely to become dehydrated (drink too little water to stay healthy).They often need a longer hospital stay than
Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Insulinoma
STANDARD TREATMENT OPTIONS: Single lesion in head of pancreas or single lesion less than 1.0 cm in tail of pancreas: Enucleation,if feasible. Single lesion in body/tail greater than 1.0 cm: Distal pancreatectomy. Multiple lesions: occur in 10%,suspect multiple endocrine neoplasia syndrome type 1 (MEN-1): Resect body and tail. Metastatic lesions-lymph nodes or distant sites: Resect when ...
Gonzalez Regimen (PDQ®): Complementary and alternative medicine - Health Professional Information [NCI] - Overview
This complementary and alternative medicine (CAM) information summary provides an overview of the Gonzalez regimen as a treatment for cancer. The summary includes a brief history of the science and philosophies of care that have influenced development of the regimen,the results of research and clinical studies,and side effects that have been associated with this treatment approach. This ...
Colon Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Changes to This Summary (03 / 28 / 2012)
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Changes were made to this summary to match those made to the health professional version.
Treatment of Recurrent Childhood High-Grade Astrocytomas
Most patients with high-grade astrocytomas or gliomas will eventually have tumor recurrence, usually within 3 years of original diagnosis but perhaps many years after initial treatment. Disease may recur at the primary tumor site, at the margin of the resection/radiation bed, or at noncontiguous central nervous system sites. Systemic relapse is rare but may occur. At the time of recurrence, a complete evaluation for extent of relapse is indicated for all malignant tumors. Biopsy or surgical resection may be necessary for confirmation of relapse because other entities, such as secondary tumor and treatment-related brain necrosis, may be clinically indistinguishable from tumor recurrence. The need for surgical intervention must be individualized on the basis of the initial tumor type, the length of time between initial treatment and the reappearance of the mass lesion, and the clinical picture. Patients for whom initial treatment fails may benefit from additional treatment.
Prostate Cancer Screening (PDQ®): Screening - Health Professional Information [NCI] - Evidence of Benefit
Prior to the 1990s,the digital rectal examination (DRE) was the test traditionally mentioned for prostate cancer screening. Two other test procedures are also available: transrectal ultrasound (TRUS) imaging and serum prostate-specific antigen (PSA) concentrations.[ 1 ] Prostate cancer screening is controversial because of the lack of definitive evidence of benefit. A small randomized trial in .
Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Option Overview
How islet cell cancer is treated There are treatments for all patients with islet cell cancer. Three types of treatment are used: Surgery (taking out the cancer). Chemotherapy (using drugs to kill cancer cells). Hormone therapy (using hormones to stop cancer cells from growing). Surgery is the most common treatment of islet cell cancer. The doctor may take out the cancer and most or part of .
Spirituality in Cancer Care (PDQ®): Supportive care - Health Professional Information [NCI] - Current Clinical Trials
Check NCI's list of cancer clinical trials for U.S. supportive and palliative care trials about spiritual concerns and spiritual therapy that are now accepting participants. The list of trials can be further narrowed by location, drug, intervention, and other criteria. General information about clinical trials is also available from the NCI Web site.