Oral Cancer (Mouth Cancer) Directory
Oral cancer can develop in any part of the mouth, including on the lips, tongue, cheeks, floor of the mouth, roof of the mouth, sinuses, and throat. Risk factors for oral cancer include smoking or spit (chewing) tobacco and excessive use of alcohol. Oral cancer can be life threatening if not diagnosed and treated early. It is important to check regularly for symptoms of oral cancer, such as a growth or sore in the mouth that does not go away. If you see something that looks suspicious, make an appointment with a dentist as soon as possible. Follow the links below to find WebMD's comprehensive coverage about how oral cancer is contracted, what it looks like, how to treat it, and much more.
Oral Complications of Chemotherapy and Head/Neck Radiation (PDQ®): Supportive care - Health Professional Information [NCI]-Graft-versus-Host Disease
Patients who have received allogeneic or matched unrelated transplants are at risk of developing graft-versus-host disease (GVHD).[1,2] A related condition referred to as pseudo-GVHD is occasionally reported in autologous hematopoietic stem cell transplant recipients. GVHD can affect oral tissues and often mimics naturally occurring autoimmune diseases such as erosive lichen planus, pemphigus, scleroderma, and Sjögren syndrome. Oral GVHD has also been linked to oral precancerous and malignant lesions.Acute GVHD can occur as early as 2 to 3 weeks posttransplant; mucosal erythema and erosion/ulceration are typical manifestations. Chronic oral GVHD changes can be recognized as early as day 70 posttransplant. The pattern and types of lesions seen in acute GVHD are also seen in chronic GVHD, but manifestations can also include raised white hyperkeratotic plaques and striae and persistent reduced salivary function. Oral symptoms of oral GVHD include xerostomia and increased
Oral Complications of Chemotherapy and Head/Neck Radiation (PDQ®): Supportive care - Patient Information [NCI]-Oral Complications and Their Causes
Cancer treatment can cause mouth and throat problems.Complications of chemotherapy Oral complications caused by chemotherapy include the following:Inflammation and ulcers of the mucous membranes in the stomach or intestines.Easy bleeding in the mouth.Nerve damage.Complications of radiation therapyOral complications caused by radiation therapy to the head and neck include the following:Fibrosis (growth of fibrous tissue) in the mucous membrane in the mouth.Tooth decay and gum disease.Breakdown of tissue in the area that receives radiation.Breakdown of bone in the area that receives radiation.Fibrosis of muscle in the area that receives radiation.Complications caused by either chemotherapy or radiation therapyThe most common oral complications may be caused by either chemotherapy or radiation therapy. These include the following: Inflamed mucous membranes in the mouth.Infections in the mouth or that travel through the bloodstream. These can reach and affect cells all over the body.Taste
Oral Complications of Chemotherapy and Head/Neck Radiation (PDQ®): Supportive care - Health Professional Information [NCI]-Oral Mucositis
The terms oral mucositis and stomatitis are often used interchangeably at the clinical level, but they do not reflect identical processes.Oral Mucositis:Describes inflammation of oral mucosa resulting from chemotherapeutic agents or ionizing radiation.[1,2,3]Typically manifests as erythema or ulcerations.May be exacerbated by local factors.Stomatitis:Refers to any inflammatory condition of oral tissue, including mucosa, dentition/periapices, and periodontium.Includes infections of oral tissues as well as mucositis.Risk of oral mucositis has historically been characterized by treatment-based and patient-based variables. The current model of oral mucositis involves a complex trajectory of molecular, cellular, and tissue-based changes. There is increasing evidence of genetic governance of this injury,[5,6,7,8] characterized in part by upregulation of nuclear factor kappa beta and inflammatory cytokines (e.g., tumor necrosis factor-alpha) and interleukin-1 in addition to
Oral Complications of Chemotherapy and Head/Neck Radiation (PDQ®): Supportive care - Health Professional Information [NCI]-Infection
The multiple protective-barrier functions associated with normal oral mucosa directly affect risk of acute infection. Normal oral mucosa reduces levels of oral microorganisms colonizing the mucosa by shedding the surface layer; it also limits penetration of many compounds into the epithelium by maintaining a chemical barrier. Normal salivary gland function promotes mucosal health.Oral mucositis can be complicated by infection in the immunocompromised patient. Specific organisms may play a role in upregulating proinflammatory cytokines via bacterial metabolic products such as liposaccharides. Also, oral organisms can disseminate systemically in the setting of ulcerative oral mucositis and profound, prolonged neutropenia.[2,3,4,5]Both indigenous oral flora and hospital-acquired pathogens have been associated with bacteremias and systemic infection. As the absolute neutrophil count falls below 1,000/mm3, incidence and severity of infection rise. Patients with
4 Things Your Dentist Wants You to Do Now
It's easy to forget about caring for your teeth -- but it's really important to keep up your dental hygiene. Here's how -- in four easy steps.
What Your Dental Health Says About You
What can your teeth and gums tell you about your overall health? Common oral problems have been linked to heart disease, diabetes, premature birth, and more.
Oral Health: The Mouth-Body Connection
Find out why the health of your mouth just may help protect you from diseases of the body.
Don't Fear the Dentist
Millions of people fail to get necessary dental care because they're afraid to go to the dentist. Here are some tips to help you overcome your fear of the dental chair.
Slideshows & Images
Slideshow: Top Problems in Your Mouth
Sores, painful gums, bad breath -- what’s going on in your mouth? Found out with our slideshow of the most common mouth problems.
The Tongue (Human Anatomy): Picture, Function, Definition, Problems, and More
WebMD's Tongue Anatomy Page provides a detailed picture and definition of the tongue as well as an overview of its function and location in the body. Also learn about conditions, test, and procedures that may affect the tongue.
Slideshow: Surprising Ways Affects Your Looks
Pictures of twins show how smoking dramatically speeds up wrinkles and aging. Also covered: sagging breasts, early menopause, hair loss, cataracts, infertility, and other effects of smoking.
The Tonsils (Human Anatomy): Picture, Definition, Location, and Problems
WebMD's Tonsils Anatomy Page provides a detailed picture and definition of the tonsils. Also learn about their function, location in the body, and conditions that affect the tonsils.