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Cancer Health Center

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Cancer Genetics Overview (PDQ®): Genetics - Health Professional Information [NCI] - Familial Cancer Susceptibility Syndromes

Individual PDQ summaries focused on the genetics of specific cancers contain detailed information about many known cancer susceptibility syndromes. Although this is not a complete list, the following cancer susceptibility syndromes are discussed in the PDQ cancer genetics summaries (listed in parentheses following the syndromes):

  • Basal Cell Nevus Syndrome, Gorlin Syndrome, Gorlin-Goltz Syndrome, or Nevoid Basal Cell Carcinoma Syndrome (Genetics of Skin Cancer).
  • Bloom Syndrome (Genetics of Skin Cancer).
  • Breast/Ovarian Cancer, Hereditary (Genetics of Breast and Ovarian Cancer).
  • Colon Cancer, Hereditary Nonpolyposis or Lynch Syndrome (Genetics of Colorectal Cancer).
  • Cowden Syndrome (Genetics of Breast and Ovarian Cancer; Genetics of Colorectal Cancer).
  • Fanconi Anemia (Genetics of Skin Cancer).
  • Hyperparathyroidism, Familial (Genetics of Endocrine and Neuroendocrine Neoplasias).
  • Li-Fraumeni Syndrome (Genetics of Breast and Ovarian Cancer).
  • Medullary Thyroid Cancer, Familial (Genetics of Endocrine and Neuroendocrine Neoplasias).
  • Melanoma, Hereditary (Genetics of Skin Cancer).
  • Multiple Endocrine Neoplasia Type 1 (Genetics of Endocrine and Neuroendocrine Neoplasias).
  • Multiple Endocrine Neoplasia Type 2A, 2B (Sipple Syndrome) (Genetics of Endocrine and Neuroendocrine Neoplasias).
  • Paraganglioma, Hereditary (Genetics of Endocrine and Neuroendocrine Neoplasias)
  • Peutz-Jeghers Syndrome (Genetics of Colorectal Cancer; Genetics of Breast and Ovarian Cancer).
  • Polyposis, Familial Adenomatous and Attenuated Familial Adenomatous Polyposis (Genetics of Colorectal Cancer).
  • Polyposis, Familial Juvenile (Genetics of Colorectal Cancer).
  • Polyposis, MYH-Associated (Genetics of Colorectal Cancer).
  • Prostate Cancer, Hereditary (Genetics of Prostate Cancer).
  • Renal Cell Cancer, Hereditary with Uterine Leiomyomas (Genetics of Kidney Cancer [Renal Cell Cancer]).
  • Von Hippel-Lindau Syndrome (Genetics of Kidney Cancer [Renal Cell Cancer])
  • Xeroderma Pigmentosum (Genetics of Skin Cancer).

This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

WebMD Public Information from the National Cancer Institute

Last Updated: May 28, 2015
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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