Endometrial (Uterine) Cancer - Cause
The main cause of most type I endometrial cancer is too much of the hormone estrogen compared to the body's progesterone level.
Estrogen makes the lining of the uterus (endometrium) grow thicker. Progesterone "opposes" estrogen-your progesterone level goes up then drops at the end of each menstrual cycle, making the thick endometrium layer shed away. This is what you know as menstrual bleeding.
Purpose of This Summary This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about cancer-related depression and suicide risk in both the adult and the pediatric population. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions. Reviewers and Updates This summary is reviewed regularly...
Read the About This PDQ Summary article > >
When there is too much estrogen in the body, progesterone can't do its job. The endometrium gets thicker and thicker. Over time, the endometrium cells can become cancerous.
WebMD Medical Reference from Healthwise
Endometrial (Uterine) Cancer Topics
Today in Cancer
WebMD Special Sections
Health Solutions From Our Sponsors
©2005-2012 WebMD, LLC. All rights reserved.
WebMD does not provide medical advice, diagnosis or treatment. See additional information.