Stage I Adrenocortical Carcinoma

Treatment of stage I adrenocortical carcinoma is usually surgery (adrenalectomy). Lymph nodes may be removed if they are larger than normal.

Check for clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage I adrenocortical carcinoma.

Stage II Adrenocortical Carcinoma

Treatment of stage II adrenocortical carcinoma is usually surgery (adrenalectomy). Lymph nodes may be removed if they are larger than normal.

Check for clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage II adrenocortical carcinoma.

Stage III Adrenocortical Carcinoma

Treatment of stage III adrenocortical carcinoma may include the following:

• Surgery (adrenalectomy with or without removal of lymph nodes).
• A clinical trial of radiation therapy for tumors that cannot be removed by surgery.
• A clinical trial of mitotane for tumors that cannot be completely removed by surgery.

This summary section refers to specific treatments under study in clinical trials, but it may not mention every new treatment being studied. Information about ongoing clinical trials is available from the NCI Web site.

Check for clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage III adrenocortical carcinoma.

Stage IV Adrenocortical Carcinoma

Treatment of stage IV adrenocortical carcinoma may include the following as palliative therapy to relieve symptoms and improve the quality of life:

• Mitotane therapy.
• Radiation therapy to bones where cancer has spread.
• Chemotherapy followed by surgery to remove the tumor.
• Surgery to remove the tumor.
• Surgery to remove cancer from places where it has spread.
• A clinical trial of chemotherapy or biologic therapy.

This summary section refers to specific treatments under study in clinical trials, but it may not mention every new treatment being studied. Information about ongoing clinical trials is available from the NCI Web site.

Check for clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage IV adrenocortical carcinoma.