Painless swelling of one or more lymph nodes, without a recent infection.
Symptoms stemming from pressure of swollen lymph nodes on nearby organs or structures. They may include a cough, shortness of breath, abdominal pain or swelling, a Horner's syndrome (a neurological problem affecting the face and eyes, due to damage to nerves in the neck), nerve pain, and leg swelling.
Fever, either persistent or alternating with periods of normal temperatures, for 14 consecutive days or longer. These fevers usually occur twice daily, usually in the late afternoon and early evening, and rarely are greater than 102 degrees Farenheit.
Pain in lymph nodes or abdomen after drinking alcohol.
Drenching night sweats and/or chills lasting for 14 consecutive days or longer.
Unintentional weight loss (more than 10% over six months).
Increased susceptibility to infections.
Total body itching.
The symptoms of fever, chills, night sweats, and weight loss, occur in 30% of people with Hodgkin lymphoma, usually older adults. These symptoms are usually associated with a more advanced, and more aggressive, disease, with a poorer prognosis.
Staging has an important role in determining the most effective treatment for soft tissue sarcoma. Clinical staging involves magnetic resonance imaging (MRI) or computed tomography (CT) of the primary tumor area and a chest CT to look for metastasis to the lung (the most common site of distant spread). An abdominal CT scan is done in the case of retroperitoneal sarcomas because the liver may be the site of initial clinical metastasis for these tumors.
The stage is determined by the size of the...