If you are:
Only When Necessary:
No Known Risk: ACTIVE METABOLITE OF FOLIC ACID
An adult over 60:
management or monitoring precaution: Elderly at increased risk of severe gastrointestinal toxicity in combination with 5-FU.
Giving leucovorin calcium Vial to a child under 12:
management or monitoring precaution: May increase possibility of seizures in children on hydantoins.