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Interactions

Antidiabetics/Epinephrine

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

When these two medicines are taken together, epinephrine may decrease the amount of insulin that your body makes. Epinephrine may also decrease the amount of glucose that your body uses.

What might happen:

The effects of your diabetes medicine may decrease and your blood levels of glucose may increase.

What you should do about this interaction:

If you experience pale skin, blurred vision, loss of consciousness, increased thirst, increased urination, fatigue, or fast, deep breathing, contact your doctor. It may be necessary to measure your blood sugar levels more often. Your doctor may need to adjust the dose of your diabetes medicine.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

References:

1.Mayer SE. Neurohumoral transmission and the autonomic nervous system. In Gilman AG, Goodman LS, eds. Goodman and Gilman's The Pharmacological Basis of Therapeutics. 6th ed. New York: MacMillan Publishing Company. 1980.

2.Middleton E Jr, Finke SR. Metabolic response to epinephrine in bronchial asthma. J Allergy 1968 Nov;42(5):288-99.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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