Xolair subcutaneous precautions What should I know regarding pregnancy, nursing and administering Xolair subcutaneous to children or the elderly?If you are: Pregnant: Possibly Safe: THERE ARE NO ADEQUATE AND CONTROLLED TRIALS IN PREGNANT WOMEN. Nursing: Precaution: INSUFFICIENT HUMAN DATA, THOUGH EXCRETION IS EXPECTED. An adult over 60: Giving Xolair subcutaneous to a child under 12: Relative Contraindication: ANAPHYLAXIS/MALIGNANCY RISK. MIN. EFFICACY IN REDUCING ASTHMA EXACERBATION.