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Drugs & Medications

Xolair subcutaneous

GENERIC NAME(S): OMALIZUMAB

WARNINGS:

This medication can cause a very serious (sometimes fatal) allergic reaction. In many cases, this type of reaction occurred after the first dose, but it can occur with any later doses. This type of reaction usually occurred within 24 hours or up to 4 days after receiving this medication. Your health care professional will monitor you closely during treatment for any signs of an allergic reaction. Seek immediate medical attention if at any time you develop any signs of an allergic reaction including: trouble breathing, cough, chest tightness, rash, itching, swelling (especially of the throat, tongue), hives, dizziness.

If you have had an allergic reaction to omalizumab, you must never use omalizumab again.

Who should not take Xolair subcutaneous?
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Uses

This medication is used to treat moderate to severe asthma or ongoing hives from an unknown cause (chronic idiopathic urticaria-CIU) in adults and children over 12 years of age. It works by blocking your immune system's natural response to allergic triggers that can lead to an acute asthma attack or hives. This effect on your immune system (specifically immunoglobulin E-IgE) helps keep your air passages open and, over time, it keeps your asthma in better control. For CIU, omalizumab helps to reduce itching and number of hives on your skin.

This medication does not work immediately and should not be used for the quick relief of an acute asthma attack.

How to use Xolair subcutaneous

Read the Medication Guide provided by your pharmacist before you start using omalizumab and each time you get a refill. If you have any questions, consult your doctor or pharmacist.

For the treatment of asthma, this medication is injected under the skin (subcutaneously-SC) by a health care professional, usually every 2 or 4 weeks as directed by your doctor. The dosage is based on your body weight and blood level of IgE antibody, as well as your medical condition and response to therapy. Contact your doctor if you have a significant change in body weight during treatment. Your dose may need to be adjusted.

For the treatment of CIU, this medication is injected under the skin by a health care professional. It is given as directed by your doctor, usually every 4 weeks. The dosage is based on your medical condition and response to treatment.

Use this medication regularly in order to get the most benefit from it. To help you remember, use it on the same day of the week according to your schedule. It may take up to several months of continued use to see improvement in your condition.

Do not stop any of your asthma or CIU medications without consulting your doctor. Your condition may become worse if your asthma or CIU drugs are abruptly stopped. Any decrease of your medications (such as corticosteroids, antihistamines) should be done gradually, under the supervision of your doctor.

Side Effects

See also Warning section.

Injection site itching, redness, stinging, or pain may occur. Headache, leg, arm or ear pain may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: unusual lumps/growths/moles.

An allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Symptoms of an allergic reaction include: rash, hives, itching/swelling (especially of the face/tongue/throat), dizziness, chest tightness, cough, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before using omalizumab, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

Keep all medical appointments. Laboratory and/or medical tests may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

Missed Dose

For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule.

Storage

Not applicable. This medication is given in a clinic or doctor's office and will not be stored at home.

Information last revised March 2014. Copyright(c) 2014 First Databank, Inc.

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XOLAIR 150 MG VIAL
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XOLAIR 150 MG VIAL
XOLAIR 150 MG VIAL

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This medicine is a clear vial.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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