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Deep Vein Thrombosis Health Center

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Treatment for Deep Vein Thrombosis (DVT)

Treatment for deep vein thrombosis (DVT) -- a blood clot deep in a vein -- ranges from medication to self-care to surgery. Discuss treatment options with your doctor.

Goals of Treatment for DVT

There is more than one goal of treatment for deep vein thrombosis (DVT). The goals include:

  • Preventing a clot from growing
  • Preventing a clot from breaking off and traveling to the lung or another organ
  • Avoiding long-lasting complications, such as leg pain and swelling
  • Preventing blood clots from recurring

Blood Thinners for DVT

Blood thinners (also called anticoagulants) are the most common type of treatment for DVT. The main types of anticoagulants used to treat DVT’s are heparin, warfarin (Coumadin), dabigatran (Pradaxa), apixaban (Eliquis), and rivaroxaban (Xarelto).

Blood thinners can:

  • Keep a clot from growing or breaking off
  • Prevent new clots from forming

But blood thinners cannot:

  • Thin blood, despite their name
  • Dissolve an existing clot

Heparin: People with DVT may receive heparin intravenously or by injection in the hospital for several days. You may also continue the injections at home, once or twice daily. Intravenous heparin requires blood testing, but subcutaneous (under the skin) injections of low molecular weight heparin do not.

Warfarin: As a DVT treatment, you take warfarin (Coumadin) by pill once a day, beginning while you're still on heparin. Treatment may continue for three to six months or more. While on warfarin, you will need regular blood tests to ensure you have the correct dosage -- too little increases your clot risk, too much increases your risk for bleeding. Warfarin can also interact with other medicines, vitamins, or certain foods rich in vitamin K -- making regular monitoring even more important. If you're pregnant, your doctor will prescribe other types of treatment, because warfarin can cause birth defects.

Xarelto: Unlike warfarin, Xarelto does not require monitoring with blood tests. It's also less likely than warfarin to cause serious bleeding. You also do not need to worry about interactions with foods with Xarelto. The downside is that it's much more expensive than warfarin.

Pradaxa: Pradaxa is an oral anticoagulant that works by blocking a certain substance (a clotting protein called thrombin) in your blood. This helps to keep blood flowing smoothly in your body.

Eliquis: Called a selective Factor Xa inhibitor, this oral anticoagulant has also been approved to prevent strokes in some people. Usually taken twice a day, Eliquis can cause nausea, easy bruising, or minor bleeding (such as nosebleed, bleeding from cuts).

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