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Epilepsy Health Center

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Epilepsy Drugs for Children

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There are a wide number of medications available for treating epilepsy in children, and advances in the past years have made a difference. In fact, nine new drugs have become available in the last decade, says William R. Turk, MD, Chief of the Neurology Division at the Nemours Children's Clinic in Jacksonville, Florida.

But that doesn't mean the newest drug for epilepsy is the best. Turk says that while new medications have helped, there's no single miracle cure responsible for the improvements in treating epilepsy. Instead, doctors are getting better at fine-tuning treatment for each child using new and older drugs. There isn't one right medicine.

There are more than 20 medications used to treat seizures. Only some of these have been approved by the FDA for use in children. Legally, your doctor may prescribe any of the drugs. Still, it's important to be cautious about trying new adult epilepsy drugs in children until there's good evidence that they are safe in younger, small bodies. Discuss your child's options carefully with the doctor.

Types of Epilepsy Drugs

Common epilepsy drugs for partial or tonic-clonic seizures include carbamazepine (Tegretol or Carbatrol),phenytoin(Dilantin), valproate (Depakene), and valproic acid (Depakote). Side effects can include stomach problems or tiredness, and in the case of Dilantin, excess hair growth. For absence seizures, medications include Depakote or Depakene and ethosuximide(Zarontin).

Some of the newer drugs used to treat various forms of epilepsy are felbamate (Felbatol), gabapentin (Neurontin), lamotrigine (Lamictal), levetiracetam (Keppra),oxcarbazepine (Oxteller XR or Trileptil),tiagabin hydrochloride (Gabitril),topiramat (Topamax),or zonisamide (Lamictal or Zonegran). Doctors and parents met the arrival of Felbatol on the market almost 20 years ago with great excitement. It later turned out that the drug's side effects were more common and more dangerous than previously thought, but it is still a useful medicine for some people.

Some of the anti-seizure medications -- like Depakote -- have been approved as monotherapy for children. This means that it could be the only epilepsy drug your child would take. Many children may prefer monotherapy, because they only have to remember to take one pill.

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