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Multiple Sclerosis Health Center

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How Multiple Sclerosis Is Diagnosed

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It can be a challenge for doctors to diagnose multiple sclerosis (MS). There’s no one test that can definitely show if someone has it. And there are many conditions with symptoms that can seem like MS.

But a neurologist who specializes in treating the disease should be able to look into how you’re feeling and help you figure out if your symptoms mean you have MS or another problem.

Getting a Diagnosis

Your doctor will start by asking you about your medical history and your symptoms. She’ll also do a few tests to see if your brain and spinal cord are working as they should. These include:

  • Imaging tests, like an MRI, to take a closer look at your brain
  • Spinal taps, also called lumbar punctures, to check the fluid that runs through your spinal column
  • Electrical tests, called evoked potentials, to see if MS has affected your nerve pathways
  • Blood tests

What Does an MRI Show?

It's the best way for doctors to see any brain changes caused by multiple sclerosis. It can show your neurologist clear signs of inflammation in the deep parts of your brain or spinal cord that are red flags for the condition.

But older people or those with high blood pressure and diabetes also can have the same kinds of spots on a brain MRI. So your doctor will consider other info, including your symptoms, along with the scan results before she makes a diagnosis.

Also, an MRI result that says things are normal does not absolutely rule out MS. About 5% of people with multiple sclerosis don’t have lesions in the brain that show up on the test. They may have them in places that the scan can’t show.

Will I Need a Spinal Tap?

When doctors do this test, they’re looking closely at the fluid in your spine, called cerebrospinal fluid, for higher levels of proteins and other substances that are signs of the disease. These can be helpful in diagnosing MS, but they’re not absolute proof of the condition. Your doctor can tell you if you need to have a spinal tap.

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