Treatment options for patients with all stages of ovarian epithelial cancer have consisted of surgery followed by chemotherapy.SurgeryPatients diagnosed with stage III and stage IV disease are treated with surgery and chemotherapy; however, the outcome is generally less favorable for patients with stage IV disease. The role of surgery for patients with stage IV disease is unclear, but in most instances, the bulk of the disease is intra-abdominal, and surgical procedures similar to those used in the management of patients with stage III disease are applied. The options for intraperitoneal (IP) regimens are also less likely to apply both practically (as far as inserting an IP catheter at the outset) and theoretically (aimed at destroying microscopic disease in the peritoneal cavity) in patients with stage IV disease. Surgery has been used as a therapeutic modality and also to adequately stage the disease. Surgery should include total abdominal
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Editorial changes were made to this summary.
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The following is a list of ovarian epithelial cancer histologic classifications. Serous cystomas: Serous benign cystadenomas.Serous cystadenomas with proliferating activity of the epithelial cells and nuclear abnormalities but with no infiltrative destructive growth (low potential or borderline malignancy).Serous cystadenocarcinomas.Mucinous cystomas: Mucinous benign cystadenomas.Mucinous cystadenomas with proliferating activity of the epithelial cells and nuclear abnormalities but with no infiltrative destructive growth (low potential or borderline malignancy).Mucinous cystadenocarcinomas.Endometrioid tumors (similar to adenocarcinomas in the endometrium): Endometrioid benign cysts.Endometrioid tumors with proliferating activity of the epithelial cells and nuclear abnormalities but with no infiltrative destructive growth (low malignant potential or borderline malignancy).Endometrioid adenocarcinomas.Clear cell (mesonephroid) tumors: Benign clear cell tumors.Clear cell tumors with
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Editorial changes were made to this summary.This summary is written and maintained by the PDQ Adult Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.
What is an oophorectomy?Oophorectomy is the surgical removal of the ovaries, the part of a woman's reproductive system that stores and releases eggs for fertilization and produces female sex hormones. Oophorectomy is often necessary when pelvic disease, such as ovarian cancer or severe endometriosis, is present. In the United States, more than 600, 000 hysterectomies (the surgical removal of a ...