Pain Management Health Center
Pain Management: Musculoskeletal Pain
Musculoskeletal pain is pain that affects the muscles, ligaments and tendons, along with the bones.
What Causes Musculoskeletal Pain?
The causes of musculoskeletal pain are varied. Muscle tissue can be damaged with the wear and tear of daily activities. Trauma to an area (jerking movements, auto accidents, falls, fractures, sprains, dislocations, and direct blows to the muscle) also can cause musculoskeletal pain. Other causes of pain include postural strain, repetitive movements, overuse, and prolonged immobilization. Changes in posture or poor body mechanics may bring about spinal alignment problems and muscle shortening, therefore causing other muscles to be misused and become painful.
What Are the Symptoms of Musculoskeletal Pain?
People with musculoskeletal pain sometimes complain that their entire bodies ache. Their muscles may feel like they have been pulled or overworked. Sometimes the muscles twitch or burn. Symptoms vary from person to person, but the common symptoms are:
- Pain
- Fatigue
- Sleep disturbances
How Is Musculoskeletal Pain Diagnosed?
Your doctor will conduct a thorough physical examination and medical history. In addition, your doctor may perform diagnostic studies to confirm the diagnosis.
How Is Musculoskeletal Pain Treated?
Different types of manual therapy, or mobilization, can be used to treat people with spinal alignment problems. For acute musculoskeletal pain, these techniques have been shown to speed recovery.
In patients with musculoskeletal disorders such as fibromyalgia, medications to increase the body's level of serotonin and norepinephrine (neurotransmitters that modulate sleep, pain, and immune system function) are prescribed in low doses. Some of the medicines used to aid sleep include Ambien, Klonopin, and Desyrel.
Other treatments may include:
- Injections with anesthetic or anti-inflammatory medications in or around the painful sites
- Exercise that includes muscle strengthening and stretching
- Physical or occupational therapy
- Acupuncture or acupressure
- Relaxation/biofeedback techniques
- Osteopathic manipulation (a whole system of evaluation and treatment designed to achieve and maintain health by restoring normal function to the body)
- Chiropractic care
- Therapeutic massage
Reviewed by the doctors at The Cleveland Clinic Neuroscience Center.
WebMD Medical Reference provided in collaboration with the Cleveland Clinic![]()
TOPAMAX is approved for migraine prevention in adults only.
TOPAMAX is not used to stop a migraine after it starts.
IMPORTANT SAFETY INFORMATION
Serious risks associated with TOPAMAX include lowered bicarbonate levels in the blood resulting in an increase in the acidity of the blood (metabolic acidosis). Symptoms could include hyperventilation (rapid, deep breathing), tiredness, loss of appetite, irregular heartbeat or changes in the level of alertness. Call your doctor immediately if you get these symptoms. Your doctor may want to do simple blood tests. Chronic, untreated metabolic acidosis may increase the risk for kidney stones or bone disease.
Other serious risks include decreased sweating, increased body temperature, kidney stones, sleepiness, dizziness, confusion, difficulty concentrating, and increased eye pressure (glaucoma). Call your doctor immediately if you have any decrease in vision or eye pain. These problems can lead to blindness if not treated right away.
More common side effects are tingling in arms and legs, loss of appetite, tiredness, nausea, diarrhea, taste change and weight loss.
Tell your doctor about other medications you take. Please see full U.S. Prescribing Information.
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