Coenzyme Q10 May Slow Parkinson's
High Doses of Popular Supplement Delays Deterioration
Experts are quick to advise that the finding needs to be tested in more people before coenzyme Q10 supplementation can be recommended to prevent or treat Parkinson's disease.
"Am I encouraged by the study? Yes," says Abraham Lieberman, MD, professor of neurology at the University of Miami School of Medicine. "Is it interesting? Yes. Is it innovative research? Yes. Am I convinced that everyone with Parkinson's should load up on coenzyme Q10 based on this finding? No." Lieberman is also medical director of the National Parkinson's Foundation.
"Although very promising, it was a very small study but done by very good people," Lieberman tells WebMD. "It needs to be tested in larger groups before we can recommend that people with Parkinson's go out and spend $300 a month on [coenzyme Q10]in hopes it will help them."
"While tremendously encouraging, ours is only a preliminary finding and still needs to be proved in a larger study," says Shults, who presented his study at the annual meeting of the American Neurological Association. "The next step is to do that, and we're working on a proposal to study the effects of coenzyme Q10 at even higher doses."
One concern: coenzyme Q10 is chemically similar to vitamin K, which is essential for blood clotting. "So it can negate the effectiveness of 'blood-thinning' drugs like Coumadin," says Lieberman. "While there's a study using 3000 mg of coenzyme Q10 to see its effect on ALS (amyotrophic lateral sclerosis, or "Lou Gehrig's disease"), most of the studies testing coenzyme Q10 on heart disease and other conditions involve smaller doses of around 300 mg." -->