Prostate Cancer Health Center
Prostate Cancer: Prostate Ultrasound and Biopsy
Prostate ultrasound and biopsy both evaluate the abnormal results of a digital rectal exam or an elevated prostate-specific antigen (PSA) blood test.
Prostate ultrasound involves a probe about the size of a finger that is inserted a short distance into the rectum. This probe produces harmless high-frequency sound waves, inaudible to the human ear, that bounce off the surface of the prostate. The sound waves are recorded and transformed into video or photographic images of the prostate gland.
The probe can provide images at different angles to help your doctor estimate the size of your prostate and detect any abnormal growths.
A prostate biopsy uses transrectal ultrasound imaging to guide several small needles through the rectum wall into areas of the prostate where abnormalities are detected. The needles remove a tiny amount of tissue. Usually six or more biopsies are taken to test various areas of the prostate. The tissue samples are then analyzed in a laboratory. The results will help doctors diagnose disorders and diseases in the prostate. If cancer is identified the doctor will be able to grade the cancer and determine its aggressiveness or likelihood of spreading.
Some doctors perform the biopsy through the perineum (skin between the scrotum and rectum).Researchers are investigating alternative biopsy procedures in efforts to maximize the accuracy of these results.
What Happens Before The Procedure?
Here's how to get ready for the ultrasound and biopsy.
Special conditions
Tell your doctor if you have a lung or heart condition or any other diseases, or if you are allergic to any medicines.
Tell your doctor if you have an artificial heart valve or if you have ever been told you need to take antibiotics before a dental or surgical procedure. If you have any of these conditions, you will be given antibiotics to take before the biopsy.
Medications*
Tell your primary doctor if you are taking Coumadin, Persantine, Plavix or other blood thinners. With your doctor's knowledge, these medicines will need to be discontinued about one week before the procedure. Your primary doctor may prescribe an alternate method for thinning your blood before the procedure.
The week before the procedure, do NOT take aspirin, products containing aspirin, or anti-inflammatory drugs (such as Advil or Motrin, Naprosyn or Indocin).
* Please note: Do not discontinue any medication without first consulting your primary or referring physician.
You will receive antibiotics to take the night before the procedure or the morning of the procedure to prevent infection.
Eating and drinking
Eat a light breakfast or lunch before the procedure and drink only clear liquids (which include juices, broths, and gelatin) the morning of the procedure.
Enemas
You will receive one enema before the procedure to empty your colon and minimize the risk of infection during the procedure. You may be asked to use the enema at home. Try to hold the enema solution for at least five minutes before releasing it.Eat a light breakfast or lunch before the procedure and drink only clear liquids (which include juices, broths, and gelatin) the morning of the procedure.
WebMD Medical Reference provided in collaboration with the Cleveland Clinic![]()
Indication
Uroxatral® (alfuzosin HCl 10 mg extended-release tablets) is an alpha1-blocker for the treatment of the signs and symptoms of BPH.
Important Safety Information
Do not take UROXATRAL if you have liver problems or if you are taking antifungal drugs like ketoconazole or itraconazole, or HIV drugs like ritonavir.
UROXATRAL can cause a sudden drop in blood pressure, especially when starting treatment. This may lead to fainting, dizziness, and lightheadedness. Do not drive, operate machinery, or do any dangerous activity until you know how UROXATRAL will affect you. This is especially important if you already have a problem with low blood pressure or take medicines to treat high blood pressure. There may be an increased risk of low blood pressure and fainting when taking UROXATRAL in combination with blood pressure medication or nitrates, or erectile dysfunction medication.
If considering cataract surgery (clouding of the eyes), tell your eye surgeon that you are currently taking UROXATRAL or have previously been treated with an alpha-blocker.
Before taking UROXATRAL, tell your doctor if you have kidney problems.
Also, tell your doctor if you or any family member(s) have or take medications for a rare heart condition known as congenital prolongation of the QT interval.
BPH and prostate cancer can cause the same symptoms. However, UROXATRAL is not a treatment for prostate cancer.
The most common side effects with UROXATRAL are dizziness, upper respiratory tract infection, headache, and tiredness.
Please see UROXATRAL full prescribing information.

