Prostate Cancer Health Center
Orchiectomy
Orchiectomy is the removal of the testicles. The penis and the scrotum, the pouch of skin that holds the testicles, are left intact. An orchiectomy is done to stop most of the body's production of testosterone, which prostate cancer usually needs in order to continue growing.
What To Expect After Surgery
Orchiectomy can be done as an outpatient procedure or with a short hospital stay. Regular activities are usually resumed within 1 to 2 weeks, and a full recovery can be expected within 2 to 4 weeks.
Why It Is Done
Orchiectomy may help relieve symptoms, prevent complications, and prolong survival for advanced prostate cancer. Radiation treatment is sometimes needed also.
How Well It Works
Orchiectomy often causes the tumor to shrink and relieves bone pain.
This surgery does not cure prostate cancer, although it may prolong survival.
Risks
Orchiectomy causes sudden hormone changes in the body. Side effects from hormone changes include:
- Sterility.
- Loss of sexual interest.
- Erection problems.
- Hot flashes.
- Larger breasts (gynecomastia).
- Weight gain.
- Loss of muscle mass.
- Thin or brittle bones (osteoporosis)
What To Think About
Removing the testicles is one way to cut down on testosterone and other male hormones, or androgens. Taking medicine is another way to reduce androgen levels in your body. Some men may prefer surgery over taking pills or having injections. But if you choose to take medicine, you can stop taking the hormone drugs. And the side effects from taking medicine may go away. An orchiectomy is permanent.
Some men choose to have reconstructive surgery after an orchiectomy, in which the surgeon replaces the testicles with artificial testicles.
Complete the surgery information form (PDF)
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to help you prepare for this surgery.
WebMD Medical Reference from Healthwise
Indication
Uroxatral® (alfuzosin HCl 10 mg extended-release tablets) is an alpha1-blocker for the treatment of the signs and symptoms of BPH.
Important Safety Information
Do not take UROXATRAL if you have liver problems or if you are taking antifungal drugs like ketoconazole or itraconazole, or HIV drugs like ritonavir.
UROXATRAL can cause a sudden drop in blood pressure, especially when starting treatment. This may lead to fainting, dizziness, and lightheadedness. Do not drive, operate machinery, or do any dangerous activity until you know how UROXATRAL will affect you. This is especially important if you already have a problem with low blood pressure or take medicines to treat high blood pressure. There may be an increased risk of low blood pressure and fainting when taking UROXATRAL in combination with blood pressure medication or nitrates, or erectile dysfunction medication.
If considering cataract surgery (clouding of the eyes), tell your eye surgeon that you are currently taking UROXATRAL or have previously been treated with an alpha-blocker.
Before taking UROXATRAL, tell your doctor if you have kidney problems.
Also, tell your doctor if you or any family member(s) have or take medications for a rare heart condition known as congenital prolongation of the QT interval.
BPH and prostate cancer can cause the same symptoms. However, UROXATRAL is not a treatment for prostate cancer.
The most common side effects with UROXATRAL are dizziness, upper respiratory tract infection, headache, and tiredness.
Please see UROXATRAL full prescribing information.

