Some Acne Products Can Trigger Allergic Reactions
In rare instances, reactions are potentially life-threatening, agency says
By Robert Preidt
WEDNESDAY, June 25, 2014 (HealthDay News) -- Some popular over-the-counter acne treatments can cause severe irritation or even potentially life-threatening allergic reactions, the U.S. Food and Drug Administration said Wednesday.
The products contain the active ingredients benzoyl peroxide or salicylic acid and are applied to the skin. They are available as gels, lotions, face washes, solutions, cleansing pads, toners and face scrubs, the FDA said.
The products are marketed under brand names such as Proactiv, Neutrogena, MaxClarity, Oxy, Ambi, Aveeno, and Clean & Clear, the agency said.
The serious allergic reactions caused by these products differ from the less harmful potential problems -- such as dryness, itching, burning, peeling, redness and slight swelling -- already listed on the products' labels.
"There is currently no mention of the possibility of these very severe allergic reactions on the product labels," Dr. Mona Khurana, a medical officer at FDA, said in an agency news release. "It's important that consumers know about them, and that they know what to do if they occur."
To find out if an over-the-counter topical acne product contains benzoyl peroxide or salicylic acid, consumers can check the "active ingredients" section of the drug facts label on the product's package, the FDA said.
Between 1969 and the end of January 2013, the FDA received 131 reports of serious allergic reactions to these types of acne products in people ages 11 to 78. About 42 percent of the reactions occurred within minutes to 24 hours of use, the agency said.
Severe allergy symptoms such as throat tightness, shortness of breath, wheezing, low blood pressure, fainting, or collapse were experienced by patients in 40 percent of the reported cases. Other symptoms included hives, itching of the face or body, and swelling of the eyes, face and lips.
No deaths were reported, but 44 percent of the patients required hospitalization, said the FDA. The agency said it will continue to monitor and evaluate the issue and is asking manufacturers to include label information advising consumers how to test the product's safety before they use it for the first time.