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3. Your Health

Your doctor will take a careful look at your health history. Biologic drugs may not be best for people with certain health conditions, including:

  • A history of infections such as tuberculosis
  • A history of cancer
  • A weak immune system because of a disease like HIV or cancer

Biologics may cause a recurrence of some chronic diseases that are in remission. Also, because biologics suppress the immune system, they could increase your risk for serious infections.

4. Insurance Coverage

Insurance companies often want doctors to try less expensive treatments first. If those treatments don't work or you have severe psoriasis, then your insurance likely will cover the cost of a biologic drug, Murase tells WebMD.

5. Your Preferences

A biologic drug is not going to help your psoriasis if you're too afraid to take it. Biologics are given by a shot or by IV infusion. People who are terrified of needles may prefer an oral drug or topical treatment instead.

How Biologics Will Affect Your Psoriasis

Whether you start with a biologic drug or turn to one after trying other therapies, you should see dramatic results. "For the most part biologics are the [drugs] that really make the difference," Murase says.

You need to follow your doctor's instructions for any treatment carefully. See your doctor for regular follow-up visits to make sure your treatment is still working. At your visits, talk about any problems or side effects you are having.

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