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You’re Always Tired

Kidneys filter waste from your blood and ship it out in your pee. When your kidneys don’t work right, toxins can build up. One common tipoff is fatigue. You may feel spent, weak, or have trouble concentrating. Kidneys make a hormone that tells your body to create red blood cells. If you have fewer of them, your blood can’t deliver as much oxygen to your muscles and brain as they need.

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Poor Sleep

Studies show a possible link between sleep apnea and chronic kidney disease (CKD), which over time damages your organs and may lead to kidney failure. Sleep apnea may hurt your kidneys in part by preventing your body from getting enough oxygen. CKD in turn may cause sleep apnea by narrowing your throat, toxin buildup, and other ways.

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Itchy Skin

This may happen if your kidneys can’t flush out toxins and they build up in your blood.  That can cause a rash or make you itch all over. Over time, your kidneys may not be able to balance the minerals and nutrients in your body. This can lead to mineral and bone disease, which can make your skin dry and itchy.

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Swollen Face and Feet

When your kidneys can’t get rid of sodium well, fluids build up in your body. That may lead to puffy hands, feet, ankles, legs, or a puffy face. You might notice swelling especially in your feet and ankles. And protein leaking out in your urine can show up as puffiness around your eyes.

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Muscle Cramps

Cramps in your legs and elsewhere can be a sign of poor kidney function. Imbalance in the levels of sodium, calcium, potassium, or other electrolytes can interrupt how your muscles and nerves work.

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When you have kidney disease, your organs don’t make enough of a hormone called erythropoietin. The hormones signal your body to make red blood cells. Without it, you can get anemia and feel short of breath. Another cause is fluid buildup. You might have a hard time catching your breath. In serious cases, lying down may make you feel like you’re drowning.

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Foggy Head

When your kidneys don’t filter all waste out of your body, the toxins can affect your brain. Anemia also may block your brain from the oxygen it needs. You may feel dizzy and have trouble with concentration and memory. You may even become so confused that you have trouble with simple tasks.

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Low Appetite

Kidney disease can cause nausea or vomiting and upset your stomach. That may leave you with little craving for food. That sometimes may lead to weight loss.

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Foul Breath

When your kidneys can’t filter out waste, it can cause a condition called uremia. That can make your mouth smell. Also, toxins in your bloodstream can give food a metallic or off taste.

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Foamy, Brown, or Bloody Urine

Bubbly pee could be a sign of too much protein called albumin. That can result from kidney issues. So can brownish or very pale urine. Faulty kidney function also may let blood leak into your bladder. Blood in your urine also can be caused by kidney stones, tumors, or an infection.

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Sources | Medically Reviewed on 04/02/2020 Reviewed by Minesh Khatri, MD on April 02, 2020


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National Kidney Foundation: “10 Signs You May Have Kidney Disease.”

Johns Hopkins Medicine: “Chronic Kidney Disease.”

UnityPoint Health: “Are Your Kidneys Working? Recognizing and Preventing Chronic Kidney Disease: A Silent Epidemic.”

Cleveland Clinic: “Kidney Failure.”

Journal of Clinical Sleep Medicine: “Obstructive Sleep Apnea and Kidney Disease: A Potential Bidirectional Relationship?”

U.S. National Library of Medicine, Genetics Home Reference: “Action Myoclonus -- Renal Failure Syndrome.”

Merck Manual Consumer Version: “Urination, Excessive or Frequent.”

Reviewed by Minesh Khatri, MD on April 02, 2020

This tool does not provide medical advice. See additional information.

THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.