Weight loss is the most effective way to manage gout, but a low-purine diet may help you, too. Purines are natural substances in food that your body breaks down into uric acid. Too much uric acid in your blood causes gout. Some foods, like organ meats, sardines, and anchovies, have a lot of purines and can cause flare-ups. But many healthy options, like beans, lentils, and asparagus, have less. Talk to your doctor about what you can safely eat.